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Displaying results 41 - 50 of 100 in total
  1. Target

    Betaine--homocysteine S-methyltransferase 1

    go.drugbank.com/bio_entities/BE0000845
    TargetHumans

    Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline

  2. Target

    Peptide deformylase

    go.drugbank.com/bio_entities/BE0001651
    TargetStaphylococcus aureus (strain MW2)

    N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

  3. Target

    Serine hydroxymethyltransferase

    go.drugbank.com/bio_entities/BE0001753
    TargetGeobacillus kaustophilus (strain HTA426)

    This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.

  4. Target

    5,10-methylenetetrahydrofolate reductase

    go.drugbank.com/bio_entities/BE0002064
    TargetEscherichia coli (strain K12)

    Is required to provide the methyl group necessary for methionine synthetase to convert homocysteine to methionine; the methyl group is given by 5-methyltetrahydrofolate.

  5. Target

    tRNA (cytidine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase

    go.drugbank.com/bio_entities/BE0002518
    TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

    Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

  6. Target

    Peptide deformylase

    go.drugbank.com/bio_entities/BE0002535
    TargetStaphylococcus aureus

    N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).

  7. Target

    Flavodoxin/ferredoxin--NADP reductase

    go.drugbank.com/bio_entities/BE0002989
    TargetEscherichia coli (strain K12)

    Required for the activation of several enzymes such as pyruvate formate-lyase, anaerobic ribonucleotide reductase and cobalamin-dependent methionine synthase (PubMed:7042345, PubMed:8267617).

  8. Target

    Flavodoxin 1

    go.drugbank.com/bio_entities/BE0003038
    TargetEscherichia coli (strain K12)

    Involved in the reactivation of inactive cob(II)alamin in methionine synthase.

  9. Target

    Peptide deformylase

    go.drugbank.com/bio_entities/BE0003141
    TargetThermus thermophilus

    N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).

  10. Target

    Peptide deformylase

    go.drugbank.com/bio_entities/BE0003144
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).