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Displaying results 491 - 500 of 688 in total
  1. Target

    Lys-63-specific deubiquitinase BRCC36

    go.drugbank.com/bio_entities/BE0009071
    TargetHumans

    Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex (PubMed:19214193). … Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites

    Synonyms: BRCA1-A complex subunit BRCC36, BRISC complex subunit BRCC36
  2. Target

    Lysosomal alpha-glucosidase

    go.drugbank.com/bio_entities/BE0000876
    TargetEnzymeHumans

    Essential for the degradation of glycogen in lysosomes (PubMed:14695532, PubMed:18429042, PubMed:1856189, PubMed:7717400). Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans (Pub...

    Synonyms: Aglucosidase alfa
  3. Drug

    Ox bile extract

    go.drugbank.com/drugs/DB14016
    Approved

    Mixtures: Alka-pan Tablets
  4. Target

    Cytochrome b

    go.drugbank.com/bio_entities/BE0004428
    TargetPlasmodium falciparum

    Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. … The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

    Synonyms: Complex III subunit 3, Complex III subunit III
  5. Target

    Cytochrome c1, heme protein, mitochondrial

    go.drugbank.com/bio_entities/BE0003854
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.

    Synonyms: Complex III subunit 4, Complex III subunit IV
  6. Target

    Cytochrome b

    go.drugbank.com/bio_entities/BE0000938
    TargetHumans

    Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. … The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis

    Synonyms: Complex III subunit 3, Complex III subunit III
  7. Target

    D-alanine--D-alanine ligase

    go.drugbank.com/bio_entities/BE0004095
    TargetStaphylococcus aureus (strain COL)

    Cell wall formation.

    Synonyms: D-Ala-D-Ala ligase
  8. Target

    Pseudoazurin

    go.drugbank.com/bio_entities/BE0001952
    TargetAlcaligenes faecalis

    This soluble electron transfer copper protein is required for the inactivation of copper-containing nitrite reductase in the presence of oxygen.

    Synonyms: Blue copper proteinFunction: copper ion binding
  9. Target

    Afamin

    go.drugbank.com/bio_entities/BE0008979
    TargetCarrierHumans

    Functions as a carrier for hydrophobic molecules in body fluids (Probable). Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A an...

    Synonyms: ALBA
  10. Drug

    Papaya

    go.drugbank.com/drugs/DB10658
    Approved

    Papaya allergenic extract is used in allergenic testing.

    Mixtures: Alka-pan Tablets