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Poloxamer 188
go.drugbank.com/drugs/DB11333ApprovedP188 was originally approved by the FDA in the 1960s as a therapeutic agent to reduce viscosity in the blood before transfusions, however it is no longer available in any approved products [A27217]. … The ability of P188 in attenuating membrane damage and cell injury has been demonstrated in a variety of _in vivo_ and _in vitro_ models [A27218].
Categories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitorsInternational brands: Lutrol FNaftifine
go.drugbank.com/drugs/DB00735ApprovedNaftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum
International brands: A MeiProducts: DERMIFIN %1 SPREY, 20 ML, FUNDERYL %1 SPREY, 20 MLGaucher Disease, Type 1
go.drugbank.com/conditions/DBCOND0035324Synonyms: Gaucher Disease, Type 1, Type 1 Gaucher DiseaseType 1 Diabetes Mellitus
go.drugbank.com/conditions/DBCOND0029465Drugs: Donislecel · Insulin degludec · Insulin detemir · Insulin glargine · Insulin glulisine · Insulin human +3 moreSynonyms: Diabete Type 1, Type 1 DiabetesTigecycline
go.drugbank.com/drugs/DB00560ApprovedInvestigationalTigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. … Food and Drug Administration (FDA) on June 17, 2005.
Synonyms: (4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamideProducts: MRSACIN 50 MG I.V. INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON,FLAKON, 1 ADET, TIGEVITAE® 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLEAlpha-1 Anti-trypsin Deficiency
go.drugbank.com/conditions/DBCOND0066043Synonyms: Alpha-1 AT Deficiency, Alpha-1-antitrypsin-deficiencyChronic Hepatitis C Genotype 1
go.drugbank.com/conditions/DBCOND0053690Synonyms: Genotype 1, Chronic Hepatitis C Genotype 13-oxo-5-alpha-steroid 4-dehydrogenase 1
go.drugbank.com/bio_entities/BE0000539TargetEnzymeHumansCatalyzes the irreversible stereospecific reduction of the delta 4,5 bond (double bond between carbons 4 and 5) of various 3-oxo steroids (3-keto steroids) producing their 5alpha dihydro-3-oxo forms (PubMed … Converts testosterone into 5-alpha-dihydrotestosterone (DHT), a more potent androgen as it is the preferred ligand for androgen receptor (AR) transactivation, making this reaction a key step in male sexual
Polypeptides: 3-oxo-5-alpha-steroid 4-dehydrogenase 1Synonyms: Steroid 5-alpha-reductase 1, S5AR 1Deoxycholic acid
go.drugbank.com/drugs/DB03619ApprovedInvestigationalDeoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and when injected subcutaneously, it disrupts cell membranes in adipocytes and destroys fat cells in that … It is marketed under the brand name Kybella by Kythera Biopharma and is the first pharmacological agent available for submental fat reduction, allowing for a safer and less invasive alternative than surgical
Mixtures: Debiline H, Duchol EctSynonyms: (3α,5β,12α)-3,12-dihydroxycholan-24-oic acidSodium glycerophosphate
go.drugbank.com/drugs/DB09561ApprovedIt is used clinically to treat or prevent low phosphate levels [FDA Label]. Glycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body [A32667]. … The extent of this reaction is dependent on the activity of serum alkaline phosphatases.
Mixtures: NUMETA PED G 19 % E INFÜZYON IÇIN EMÜLSIYON, 1000 ML, Numeta G 13 % E Emulsion zur InfusionProducts: Glycophos 6 g/20 ml Konzentrat zur Herstellung einer Infusionslösung, GLYCOPHOS CONCENTRATE FOR SOLUTION FOR INFUSION 216 mg/ml