Search

Displaying results 5071 - 5080 of 10000 in total
  1. Drug

    Thallous chloride

    go.drugbank.com/drugs/DB09316
    ApprovedWithdrawn

    Thallous chloride (also known as Thallium(I) chloride) is a colourless solid intermediate in the isolation of thallium from its ores. … It is created from the treatment of thallium(I) sulfate with hydrochloric acid. This solid crystallizes in the caesium chloride motif. It is used as a diagnostic radiopharmaceutical.

    Synonyms: Thallium(I) chlorideProducts: TAEK-PHT 201-TlCl (TALYUM KLORÜR) 37 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 ADET, MON.TALYUM-201 IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 2 MCİ (ÇARŞAMBA KAL. PTSİ.TES)
  2. Target

    Inosine-5'-monophosphate dehydrogenase 2

    go.drugbank.com/bio_entities/BE0000722
    TargetEnzymeHumans

    Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays

    Polypeptides: Inosine-5'-monophosphate dehydrogenase 2Synonyms: Inosine-5'-monophosphate dehydrogenase type II, IMPD 2
  3. Target

    2'-5'-oligoadenylate synthase 1

    go.drugbank.com/bio_entities/BE0004585
    TargetHumans

    Catalyzes the formation of 2'-5'-oligoadenylates (2-5A) from polymerization of ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent … Can generate high levels of 2',5'-oligoadenylates in transformed cells, targeting them to innate and adaptive immunesurveillance mechanisms (PubMed:40010341).

    Polypeptides: 2'-5'-oligoadenylate synthase 1Synonyms: (2-5')oligo(A) synthase 1, 2-5A synthase 1
  4. Target

    Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

    go.drugbank.com/bio_entities/BE0002192
    TargetHumans

    Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links

    Polypeptides: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2Synonyms: Lysyl hydroxylase 2
  5. Drug

    Lanadelumab

    go.drugbank.com/drugs/DB14597
    ApprovedInvestigational

    Lanadelumab, also known as DX-2930, is a human IgG1 monoclonal antibody designed for subcutaneous self-injection. … [L4538] It is a fully human immunoglobulin, k-light-chain made in recombinant Chinese Hamster Ovary cells.

    Products: TAKHZYRO 300 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 2 ADET, TAKHZYRO 300 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET
  6. Drug

    Castor oil

    go.drugbank.com/drugs/DB11113
    ApprovedNutraceuticalVet approved

    Castor oil is a vegetable oil obtained by pressing the seeds of the castor oil plant (_Ricinus communis_ L.) mainly cultivated in India, South America, Africa, and China. … Due to its renewability and high versatility in addition to being the only commercial source of a hydroxylated fatty acid [A31170], castor oil has been used as a vital raw material for the chemical industry

    Mixtures: Polylab Surgical Spirit 98.8% v/v, HydroGold 9Products: De La Cruz Castor Oil, Huile De Ricin
  7. Drug

    Terlipressin

    go.drugbank.com/drugs/DB02638
    ApprovedInvestigational

    Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor.[A2601] It is a prodrug of [lypressin], or lysine vasopressin. … Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for the V1 receptor.

    Products: GLYPRESSIN 1 MG/8,5 ML IV ENJEKSIYONLUK COZELTI ICEREN AMPUL, 5 ADET, GLYPRESSIN 1 MG IV ENJEKSIYONLUK TOZ IÇEREN FLAKON VE ÇÖZÜCÜ AMPUL, 1 ADET
  8. Drug

    Busulfan

    go.drugbank.com/drugs/DB01008
    ApprovedInvestigational

    Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. … According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: 1, 4-Bis[methanesulfonoxy]butane
  9. Drug

    Acheta domesticus

    go.drugbank.com/drugs/DB10866
    Approved

    House cricket allergenic extract is used in allergenic testing.

    Synonyms: Acheta domesticus
  10. Drug

    Firolimogene autotemcel

    go.drugbank.com/drugs/DB18147
    Experimental

    Synonyms: CODON-OPTIMIZED HUMAN INTERLEUKIN-2 RECEPTOR SUBUNIT, AUTOLOGOUS CD34+ CELLS ISOLATED FROM BONE MARROW OF NEWLY DIAGNOSED X-LINKED SEVERE COMBINED IMMUNODEFICIENCY (X-SCID) PATIENTS, TRANSDUCED EX VIVO WITH A SELF-INACTIVATING LENTIVIRAL VECTOR, ENCODING