Search

Displaying results 501 - 510 of 1809 in total
  1. Drug

    Iodine

    go.drugbank.com/drugs/DB05382
    ApprovedInvestigational

    Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.

    Mixtures: Vita-vim - Tab, Viva Kids Plus, Tablet
  2. Drug

    Capsaicin

    go.drugbank.com/drugs/DB06774
    ApprovedInvestigational

    The most recent capsaicin FDA approval was Qutenza, an 8% capsaicin patch dermal-delivery system, indicated for neuropathic pain associated with post-herpetic neuralgia.

    Mixtures: Better Nature Pain Relief CreamProducts: Better Nature Pain Relief BalmX
  3. Target

    5-hydroxytryptamine receptor 4

    go.drugbank.com/bio_entities/BE0000084
    TargetHumans

    G protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:10821780, PubMed:16102731, PubMed:35714614, PubMed … Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors (PubMed:16102731, PubMed:35714614

    Polypeptides: 5-hydroxytryptamine receptor 4Synonyms: Serotonin receptor 4
  4. Target

    B-cell receptor CD22

    go.drugbank.com/bio_entities/BE0000183
    TargetHumans

    Acts as an inhibitory coreceptor on the surface of B-cells and inhibits B-cell receptor induced signaling, characterized by inhibition of the calcium mobilization and cellular activation.

    Polypeptides: B-cell receptor CD22Function: CD4 receptor binding
  5. Target

    Retinoic acid receptor beta

    go.drugbank.com/bio_entities/BE0000206
    TargetHumans

    Receptor for retinoic acid.

    Polypeptides: Retinoic acid receptor betaSynonyms: Nuclear receptor subfamily 1 group B member 2
  6. Target

    Muscarinic acetylcholine receptor M5

    go.drugbank.com/bio_entities/BE0000247
    TargetHumans

    The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action

    Polypeptides: Muscarinic acetylcholine receptor M5Function: G protein-coupled acetylcholine receptor activity
  7. Target

    Alpha-2C adrenergic receptor

    go.drugbank.com/bio_entities/BE0000342
    TargetHumans

    Alpha-2 adrenergic receptors are G protein-coupled receptors for catecholamines that activate the G(i/o) protein pathway, thereby promoting adenylyl cyclase inhibition, ERK1/2 stimulation, and voltage-gated calcium channels suppression (...

    Polypeptides: Alpha-2C adrenergic receptorSynonyms: Alpha-2 adrenergic receptor subtype C4
  8. Target

    5-hydroxytryptamine receptor 2B

    go.drugbank.com/bio_entities/BE0000393
    TargetHumans

    G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:18703043, PubMed:23519210, PubMed:7926008, PubMed:8078486, PubMed:8143856, PubMed:8882600). … Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways (PubMed:23519215, PubMed:28129538, PubMed:30127358, PubMed:36087581).

    Polypeptides: 5-hydroxytryptamine receptor 2BSynonyms: Serotonin receptor 2B
  9. Target

    Somatostatin receptor type 1

    go.drugbank.com/bio_entities/BE0000452
    TargetHumans

    Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. … In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins

    Polypeptides: Somatostatin receptor type 1
  10. Target

    5-hydroxytryptamine receptor 1F

    go.drugbank.com/bio_entities/BE0000460
    TargetHumans

    Receptor for lasmiditan, a drug for the treatment of acute migraine (PubMed:34239069). … Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase (PubMed

    Polypeptides: 5-hydroxytryptamine receptor 1FSynonyms: Serotonin receptor 1F