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Milrinone
go.drugbank.com/drugs/DB00235ApprovedInvestigationalHeart failure is a multifactorial condition that affects roughly 1-2% of the adult population. … [A228333] It was approved by the FDA on December 31, 1987, and was marketed under the trademark PRIMACOR® by Sanofi-Aventis US before being discontinued.[L31483]
Synonyms: 1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrileCategories: Heterocyclic Compounds, 1-RingMometasone furoate
go.drugbank.com/drugs/DB14512ApprovedInvestigationalVet approvedIt has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than many other corticosteroids as well[A176906]. … Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications[FDA Label][F4292,F4295].
Mixtures: M-FURO FA %0.1 + %2 KREM, 30 G, MATEC 2/200 MCG INHALASYON TOZ IÇEREN KAPSÜL , 120 KAPSÜLProducts: Monovo 1 mg/g Creme, Momecutan 1 mg/g CremeCefadroxil
go.drugbank.com/drugs/DB01140ApprovedInvestigationalVet approvedWithdrawnLong-acting, broad-spectrum, water-soluble, cephalexin derivative.
Categories: Heterocyclic Compounds, 2-RingProducts: CEFRADUR 1 G TABLET, 20 ADET, CEFRADUR 250 MG/5 ML ORAL SÜSPANSİYON HAZIRLAMAK İÇİN KURU TOZ, 60 MLCyclosporine
go.drugbank.com/drugs/DB00091ApprovedInvestigationalVet approved[A174049] Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
Products: Vanquoral 10 mg Weichkapseln, Sandimmun Neoral 10 mg - KapselnDolutegravir
go.drugbank.com/drugs/DB08930ApprovedInvestigational[L1035] On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named … [A31342] Dolutegravir was developed by ViiV Healthcare and FDA-approved on August 12, 2013.
Mixtures: TRIUMEQ 50 MG/600 MG/300 MG FILM KAPLI TABLET,90 FILM KAPLI TABLET, TRIUMEQ 50 MG/600 MG/300 MG FILM KAPLI TABLET,FILM KAPLI TABLET, 30 ADETCategories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingMethadone
go.drugbank.com/drugs/DB00333ApprovedInvestigationalThe intention of substitution of illicit opioids with the long-acting opioids used in OAT is to prevent withdrawal symptoms for 24-36 hours following dosing to ultimately reduce cravings and drug-seeking … However, it also has a unique pharmacokinetic profile.
Products: Methasan 20 mg-Tabletten, Methasan 10 mg-TablettenEzetimibe
go.drugbank.com/drugs/DB00973ApprovedInvestigational[A33313] In genetically NPC1L1-deficient mice, a 70% reduction in intestinal cholesterol absorption was seen, and these mice were insensitive to ezetimibe treatment - it was determined based on these findings … C1-Like 1 (NPC1L1), and is unique in that it does not affect the absorption of fat-soluble nutrients such as fat-soluble vitamins, triglycerides, or bile acids.
Mixtures: VYTORIN ® 10/20 MG, VYTORIN ® 10/20 MGCategories: Heterocyclic Compounds, 1-RingAzelaic acid
go.drugbank.com/drugs/DB00548ApprovedInvestigationalAzelaic acid is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. … It is also produced by _Malassezia furfur_, also known as _Pityrosporum ovale_, which is a species of fungus that is normally found on human skin.
Mixtures: Azelaic Acid 15% / Niacinamide 4%, 2% Salicylic Acid FACIAL CLEANSERProducts: AZELDERM %20 KREM (30 G), Finacea 150 mg/g GelClindamycin
go.drugbank.com/drugs/DB01190ApprovedInvestigationalVet approved[L11593] It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and bacilli and gram-negative bacilli. … Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris.
Mixtures: OXIMIN 10 MG/G + 50 MG/G JEL,25 G, OXIMIN 10 MG/G + 50 MG/G JEL,50 GCategories: Heterocyclic Compounds, 1-RingMavacamten
go.drugbank.com/drugs/DB14921ApprovedInvestigational[A248440] Mavacamten was also approved by Health Canada in October 2022 and by EMA in July 2023 for the same indication.[L44106,L47471]
Synonyms: 6-(((1S)-1-Phenylethyl)amino)-3-(propan-2-yl)-1,2,3,4 tetrahydropyrimidine-2,4-dioneCategories: Heterocyclic Compounds, 1-Ring