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Pyridostigmine
go.drugbank.com/drugs/DB00545ApprovedInvestigational[A231009, A231014, L32413, L32418] Pyridostigmine was granted initial FDA approval on April 6, 1955, as an oral tablet. … Myasthenia gravis is an autoimmune disease involving dysfunction at the neuromuscular junction, most commonly due to autoantibodies directed against the acetylcholine receptor (AChR), which results in
International brands: Kalymin NCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP3A InducersIsopropyl alcohol
go.drugbank.com/drugs/DB02325ApprovedInvestigationalAn isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
Synonyms: 2-PropanolMixtures: P-Care MG, Physicians EZ Use B-12 ComplianceCefditoren
go.drugbank.com/drugs/DB01066ApprovedCefditoren is an oral third-generation cephalosporin. It is commonly marketed under the trade name Spectracef by Cornerstone BioPharma.
Categories: Heterocyclic Compounds, 2-RingProducts: CEFITEN 50 MG SASE, 21 ADET, CEFITEN 50 MG SASE, 42 ADETTiopronin
go.drugbank.com/drugs/DB06823ApprovedIt is similar to d-penicillamine in use and efficacy, but offers the advantage of far less adverse effects. … It has been investigated for use in the treatment of arthritis and as a neuroprotective agent in aneurysmal subarachnoid hemorrhage.
International brands: Kai NaCategories: N-substituted GlycinesDeferasirox
go.drugbank.com/drugs/DB01609ApprovedInvestigationalDeferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload in patients receiving long term blood transfusions.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingProducts: DEFERASIROX EG, RASIROX® 500 MGRetinol dehydrogenase 5
go.drugbank.com/bio_entities/BE0000570TargetEnzymeHumansCatalyzes the oxidation of cis-isomers of retinol, including 11-cis-, 9-cis-, and 13-cis-retinol in an NAD-dependent manner (PubMed:10588954, PubMed:11675386, PubMed:9115228, PubMed:9931293). Has no activity towards all-trans retinal (By...
Polypeptides: Retinol dehydrogenase 5Synonyms: Short chain dehydrogenase/reductase family 9C member 5Peroxiredoxin-5, mitochondrial
go.drugbank.com/bio_entities/BE0000907TargetEnzymeHumansThiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor o...
Polypeptides: Peroxiredoxin-5, mitochondrialSynonyms: Alu corepressor 1, Thioredoxin-dependent peroxiredoxin 55-aminolevulinate synthase
go.drugbank.com/bio_entities/BE0002158TargetHumansCatalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products.
Polypeptides: 5-aminolevulinate synthaseSynonyms: 5-aminolevulinic acid synthaseIntegrin alpha-5
go.drugbank.com/bio_entities/BE0008988TargetHumansIntegrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. … ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1
Polypeptides: Integrin alpha-5Synonyms: VLA-5Thyroxine 5-deiodinase
go.drugbank.com/bio_entities/BE0009333TargetEnzymeHumansT1), rT3 to 3',5'-diiodothyronine (3',5'-T2) and 3,3'-T2 to 3'-monoiodothyronine (3'-T1) via inner-ring deiodination (IRD) (PubMed:7593630, PubMed:12586771, PubMed:12746313, PubMed:18821722, PubMed:18339710 … Catalyzes the deiodination of L-thyroxine (T4) to 3,3',5'-triiodothyronine (rT3), 3,5,3'-triiodothyronine (T3) to 3,3'-diiodothyronine (3,3'-T2), 3,5-diiodothyronine (3,5-T2) to 3-monoiodothyronine (3-
Polypeptides: Thyroxine 5-deiodinaseFunction: thyroxine 5'-deiodinase activity