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Trimethoprim
go.drugbank.com/drugs/DB00440ApprovedInvestigationalVet approved[L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of
Mixtures: EUSAPRIM K SUS F KDR, TRIMETROPINA SULFA F MKAvalglucosidase alfa
go.drugbank.com/drugs/DB16099ApprovedInvestigational[A232955] Avalglucosidase alfa is a recombinant form of GAA that restores deficient enzyme levels. … [L35160] Avalglucosidase alfa was approved by Health Canada on November 15, 2021 for the treatment of patients older than six months of age with late-onset Pompe disease.
Diclofenac
go.drugbank.com/drugs/DB00586ApprovedInvestigationalVet approvedDiclofenac was first approved by the FDA in July 1988 under the trade name Voltaren, marketed by Novartis (previously Ciba-Geigy).[L7360]
Products: Up and Up Arthritis Pain Reliever, K-FECDOLThyroid, porcine
go.drugbank.com/drugs/DB09100ApprovedInvestigational[A190831,L11755] Thyroid extract has been described in literature to treat hypothyroidism since 1891[A190807] but its use dates back as far as the 6th century.
Elasomeran
go.drugbank.com/drugs/DB15654ApprovedInvestigational[L39160, L39277] A similar booster dose is also available in the US for patients 18 years of age and older. … For the 2024-2025 season, an updated formulation was approved for use in Canada and the US to target the Omicron KP.2 subvariant.[L51404,L40074]
Cycloserine
go.drugbank.com/drugs/DB00260ApprovedInvestigationalAntibiotic substance produced by Streptomyces garyphalus.
Colfosceril palmitate
go.drugbank.com/drugs/DB09114ApprovedWithdrawn[T70] It was developed by Burroughs Wellcome and it was FDA approved on August 6, 1990.[L1109] Nowadays colfosceril palmitate is under the state of canceled post-marketing.
Vibrio cholerae CVD 103-HgR strain live antigen
go.drugbank.com/drugs/DB14443ApprovedInvestigational[L12801] Cholera is an acute bacterial disease of the small intestine caused by _Vibrio cholerae_, which is gram-negative bacteria. … [A244494] Vaxchora was later approved by the European Commission in April 2020.[L39729] It is indicated for individuals aged two years and older.[L12801]
Palivizumab
go.drugbank.com/drugs/DB00110ApprovedInvestigationalThe human lightchain sequence was derived from the constant domain of Ck and the variable framework regions of the VL gene K104 withJk-4. … Humanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV).
Coagulation factor VIIa Recombinant Human
go.drugbank.com/drugs/DB00036ApprovedInvestigationalNovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form. … Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade.