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Interleukin-21 receptor
go.drugbank.com/bio_entities/BE0010657TargetHumansThis is a receptor for interleukin-21
Synonyms: IL-21R, IL-21 receptorInterleukin-21
go.drugbank.com/bio_entities/BE0010474TargetHumansCytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). Implicated in the generation and maintenance of T follicula...
Synonyms: IL-21Interleukin-13 receptor subunit alpha-2
go.drugbank.com/bio_entities/BE0002421TargetHumansFunctions as a decoy receptor that inhibits IL-13- and IL-4-mediated signal transduction via the JAK-STAT pathway and thereby modulates immune responses and inflammation (PubMed:11861389, PubMed:17030238 … Cell surface receptor that plays a role in the regulation of IL-13-mediated responses (PubMed:11861389, PubMed:17030238).
Synonyms: IL-13RA2, IL-13R-alpha-2Interleukin-1 receptor type 2
go.drugbank.com/bio_entities/BE0009549TargetHumansNon-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association w...
Synonyms: IL-1R-2, IL-1RT2Interleukin-13
go.drugbank.com/bio_entities/BE0002438TargetHumansCytokine that plays important roles in allergic inflammation and immune response to parasite infection (PubMed:8096327, PubMed:8097324). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). Stimulates B-cell pro...
Synonyms: IL-13Doxorubicin
go.drugbank.com/drugs/DB00997ApprovedInvestigationalcumulative dose is reached. … Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.
Synonyms: (1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside, (8S-cis)-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedioneCategories: Topoisomerase II InhibitorsSuccinylcholine
go.drugbank.com/drugs/DB00202ApprovedInvestigational[A19054] It has been widely used for over 50 years,[A299] most commonly in its chloride salt form, as a means of neuromuscular blockade during intubation and surgical procedures. … Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter [acetylcholine] (ACh) linked by their acetyl groups.
Products: Suxamethonium Aguettant 10 mg/ml Injektionslösung in einer Fertigspritze, Anectine Inj 20mg/mlTrabectedin
go.drugbank.com/drugs/DB05109ApprovedInvestigationalIt is approved for use in Europe, Russia and South Korea for the treatment of advanced soft tissue sarcoma. … It is currently under evaluation for the treatment of breast cancer, prostate cancer, in addition to pediatric sarcomas. Both the European Commission and the U.S.
Products: YONDELIS 1 MG IV KONSANTRE INFUZYONLUK COZELTI ICIN TOZInterleukin-23
go.drugbank.com/bio_entities/BE0008663TargetHumansPromotes the expansion and survival of T-helper 17 cells, a CD4-positive helper T-cell subset that produces IL-17, as well as other IL-17-producing cells (PubMed:17676044) … Associates with IL12B to form the pro-inflammatory cytokine IL-23 that plays different roles in innate and adaptive immunity (PubMed:11114383).
Synonyms: IL-12B, IL-23-AInterleukin-2 receptor subunit beta
go.drugbank.com/bio_entities/BE0000651TargetHumansReceptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (...
Synonyms: IL-2RB, IL-2R subunit beta