Search
Mavacamten
go.drugbank.com/drugs/DB14921ApprovedInvestigationalMavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (HCM). … It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans.
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesSynonyms: 6-(((1S)-1-Phenylethyl)amino)-3-(propan-2-yl)-1,2,3,4 tetrahydropyrimidine-2,4-dioneWater
go.drugbank.com/drugs/DB09145ApprovedInvestigationalWater is a liquid at standard ambient temperature and pressure, but it often co-exists on Earth with its solid state, ice; and gaseous state, steam (water vapor). … As a chemical compound, a water molecule contains one oxygen and two hydrogen atoms that are connected by covalent bonds.
Mixtures: ORAZOLE ® 10 MG CAPSULA, ENOXAPARINA SODICA 40 MG JERINGAS PRELLENADASProducts: N/A, A-MedDry Eyes
go.drugbank.com/conditions/DBCOND0054254Drugs: Acrylic Acid · Carbomer · Carbomer homopolymer type C · Carbopol 974P · Carboxymethylcellulose · Chamomile +12 moreSynonyms: Vitamin A deficiency with xerophthalmia, Other ocular manifestations of vitamin A deficiencyAlteplase
go.drugbank.com/drugs/DB00009ApprovedInvestigationalAlteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent.[L43125] It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. … [A252330,L43125] Alteplase is a purified glycoprotein of 527 amino acids expressed in Chinese hamster ovary (CHO) cells.
Synonyms: t-PA, r-tPAMixtures: Activase RT-PA, Lysatec RT - PaDanazol
go.drugbank.com/drugs/DB01406ApprovedInvestigationalA synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. … Danazol has been used in the treatment of endometriosis and some benign breast disorders.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: CIPLADANOGEN® 200 MG CAPSULAS, DANAZOL 100 MGBasiliximab
go.drugbank.com/drugs/DB00074ApprovedInvestigationalIt is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell line genetically engineered to express plasmids containing the human heavy and light chain constant region genes … A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also
Categories: Interleukin-2 Receptor Antagonist, Interleukin-2 Receptor Blocking AntibodyProducts: SIMULECT® LIOFILIZADO PARA INYECCION 20 MG/VIAL, SIMULECT 20 MG İNFÜZYON VEYA ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADETRibociclib
go.drugbank.com/drugs/DB11730ApprovedInvestigationalRibociclib is a selective cyclin-dependent kinase inhibitor, a class of drugs that help slow the progression of cancer by inhibiting two proteins called cyclin-dependent kinase 4 and 6 (CDK4/6). … Ribociclib was approved by the FDA in March 2017 under the brand name Kisqali.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesProducts: KISQALI (200 MG), KISQALI 200 MG TABLETAS RECUBIERTASTofacitinib
go.drugbank.com/drugs/DB08895ApprovedInvestigationalTofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. … Known adverse effects include nausea and headache as well as more serious immunologic and hematological adverse effects. Tofacitinib is marketed under the brand name Xeljanz by Pfizer.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: JANTY 5 MG FİLM KAPLI TABLET, 56 ADET, TOFİK 5 MG FİLM KAPLI TABLET, 56 ADETSelinexor
go.drugbank.com/drugs/DB11942ApprovedInvestigationalSelinexor is a first-in-class selective inhibitor of nuclear transport (SINE) compound. … Selinexor, in combination with [bortezomib] and [dexamethasone], is currently approved for the treatment of multiple myeloma, a type of cancer formed from antibody-producing plasma cells.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Nexpovio 20 mg Film Kaplı Tablet, 8 TABLET, Nexpovio 20 mg Film Kaplı Tablet, 12 TABLETCalcium ascorbate
go.drugbank.com/drugs/DB14483ApprovedNutraceuticalMixtures: Adrien Gagnon Formule A-C-E + Selenium, Vitamin A C E W.niacinam.beta Car.and Min.Categories: Compounds used in a research, industrial, or household setting, Vitamin C and analogues