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Displaying results 5321 - 5330 of 10000 in total
  1. Drug

    Coal tar

    go.drugbank.com/drugs/DB11082
    Approved

    Coal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas.

    Mixtures: PREPARED COAL TAR 5% ET SALICYLIC ACID 2% OINTMENT, Multi-action Denorex 2-IN-1 Dandruff Shampoo + ConditionerProducts: Estar Gel 5%, Tar Doak Lotion 5%
  2. Drug

    Brexpiprazole

    go.drugbank.com/drugs/DB09128
    ApprovedInvestigational

    It also displays stronger antagonism at the 5-HT1A and 5-HT2A receptors.[A182186, A38385, A259661] Brexpiprazole was first approved by the FDA on July 10, 2015. … Brexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called serotonin-dopamine activity modulator (SDAM).

    Categories: MATE 2 Inhibitors, Dopamine D2 Receptor AgonistsSynonyms: Lu-AF41156
  3. Drug

    RO-6870810

    go.drugbank.com/drugs/DB15151
    Investigational

    RO-6870810 is under investigation in clinical trial NCT02308761 (A Study of RO6870810/TEN-010 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndrome).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-[(4S)-6-(4-chlorophenyl)-1,7,8-trimethylthiophenol[3,2-f]1,2,4-triazolo[4,3-a]1,4-diazepin-4-yl]-N-[3-(4-methylpiperazinyl)propyl]acetamide, 6H-THIENO(3,2-F)(1,2,4)TRIAZOLO(4,3-A)(1,4)DIAZEPINE-6-ACETAMIDE, 4-(4-CHLOROPHENYL)-2,3,9-TRIMETHYL-N-(3-(4-METHYL-1-PIPERAZINYL)PROPYL)-, (6S)-
  4. Drug

    Efepoetin alfa

    go.drugbank.com/drugs/DB19197
    Investigational

    Efepoetin alfa is under investigation in clinical trial NCT04155125 (A Study of Efepoetin Alfa in Treating Anaemia Associated With Chronic Kidney Diseases Patient).

    Synonyms: Human erythropoietin (epoetin alfa) fused to a hybrid human immunoglobulin (ig), consisting of the fc fragment of the igg4 fused to the hinge and amino-terminus of the igd heavy chain isotype 2, produced
  5. Drug

    Clervonafusp alfa

    go.drugbank.com/drugs/DB17623
    Investigational

    Synonyms: Immunoglobulin g1-kappa, cell-penetrating humanized fab fragment targeting the equilibrative nucleoside transporter 2 (ent2), fused with a human lysosomal .alpha.-glucosidase fragment, glycoform alfa, Immunoglobulin g1, (humanized monoclonal 3e10 .gamma.1-chain fab fragment) fusion protein with 67-952-lysosomal .alpha.
  6. Drug

    Ethanol

    go.drugbank.com/drugs/DB00898
    ApprovedInvestigational

    A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. … It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.

    Mixtures: Prosera Soothing Hand Sanitizer, De La Cruz Tincture of IodineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers
  7. Drug

    Mometasone furoate

    go.drugbank.com/drugs/DB14512
    ApprovedInvestigationalVet approved

    Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. … It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than many other corticosteroids as well[A176906].

    Mixtures: M-FURO FA %0.1 + %2 KREM, 30 G, HEXALER DUOCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers
  8. Target

    Retinol dehydrogenase 5

    go.drugbank.com/bio_entities/BE0000570
    TargetEnzymeHumans

    Catalyzes the oxidation of cis-isomers of retinol, including 11-cis-, 9-cis-, and 13-cis-retinol in an NAD-dependent manner (PubMed:10588954, PubMed:11675386, PubMed:9115228, PubMed:9931293). Has no activity towards all-trans retinal (By...

    Polypeptides: Retinol dehydrogenase 5Synonyms: Short chain dehydrogenase/reductase family 9C member 5
  9. Target

    Peroxiredoxin-5, mitochondrial

    go.drugbank.com/bio_entities/BE0000907
    TargetEnzymeHumans

    Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor o...

    Polypeptides: Peroxiredoxin-5, mitochondrialSynonyms: Thioredoxin-dependent peroxiredoxin 5
  10. Target

    5-aminolevulinate synthase

    go.drugbank.com/bio_entities/BE0002158
    TargetHumans

    Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products.

    Polypeptides: 5-aminolevulinate synthaseSynonyms: 5-aminolevulinic acid synthase