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Displaying results 5331 - 5340 of 10000 in total
  1. Target

    Integrin alpha-5

    go.drugbank.com/bio_entities/BE0008988
    TargetHumans

    Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. … ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1

    Polypeptides: Integrin alpha-5Synonyms: VLA-5
  2. Target

    Thyroxine 5-deiodinase

    go.drugbank.com/bio_entities/BE0009333
    TargetEnzymeHumans

    T1), rT3 to 3',5'-diiodothyronine (3',5'-T2) and 3,3'-T2 to 3'-monoiodothyronine (3'-T1) via inner-ring deiodination (IRD) (PubMed:7593630, PubMed:12586771, PubMed:12746313, PubMed:18821722, PubMed:18339710 … Catalyzes the deiodination of L-thyroxine (T4) to 3,3',5'-triiodothyronine (rT3), 3,5,3'-triiodothyronine (T3) to 3,3'-diiodothyronine (3,3'-T2), 3,5-diiodothyronine (3,5-T2) to 3-monoiodothyronine (3-

    Polypeptides: Thyroxine 5-deiodinaseFunction: thyroxine 5'-deiodinase activity
  3. Target

    Pseudouridine-5'-phosphatase

    go.drugbank.com/bio_entities/BE0014361
    EnzymeHumans

    Dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine

    Polypeptides: Pseudouridine-5'-phosphataseSynonyms: 5'-PsiMPase, Pseudouridine-5'-monophosphatase
  4. Target

    NADPH oxidase 5

    go.drugbank.com/bio_entities/BE0018640
    TargetHumans

    Also synthesizes NAADP from its reduced NAADPH form which promotes Ca(2+) signaling during T cell activation (PubMed:34784249). May play a role in cell growth and apoptosis (PubMed:12686516)

    Polypeptides: NADPH oxidase 5
  5. Target

    Camphor 5-monooxygenase

    go.drugbank.com/bio_entities/BE0001246
    TargetPseudomonas putida

    Involved in a camphor oxidation system.

    Polypeptides: Camphor 5-monooxygenaseFunction: camphor 5-monooxygenase activity
  6. Drug

    Doxepin

    go.drugbank.com/drugs/DB01142
    ApprovedInvestigational

    [T559] It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to [cidoxepin]. Doxepin commonly produces a 5:1 (E):(Z) racemic mixture. … [T83] In a strict sense, doxepin is not a tricyclic antidepressant but it is commonly associated with the class since it shares a lot of properties with members of the drug family including [amitriptyline

    Categories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsProducts: PURDOX %5 KREM, 30 G, EXPAN® 50 MG
  7. Drug

    Gonadorelin

    go.drugbank.com/drugs/DB00644
    ApprovedInvestigationalVet approved

    It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pituitary.

    Products: LH-RH FERRING 0,1 MG/ML IV ENJEKSIYONLUK COZELTI ICEREN AMPUL, 1 ADET, Kryptocur 0,2 mg/0,1 ml - nasale Sprühlösung
  8. Drug

    Ethanol

    go.drugbank.com/drugs/DB00898
    ApprovedInvestigational

    A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. … It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.

    Synonyms: 1-HydroxyethaneMixtures: Prosera Soothing Hand Sanitizer, De La Cruz Tincture of Iodine
  9. Drug

    Tenoxicam

    go.drugbank.com/drugs/DB00469
    ApprovedInvestigational

    Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.

    Categories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesProducts: TİCOTEN 20 MG/2 ML I.M./I.V. ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 ADET, OKSAMEN-L 20 MG IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ (1 FLAKON, 1 AMPUL)
  10. Drug

    Dapsone

    go.drugbank.com/drugs/DB00250
    ApprovedInvestigational

    A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)

    Synonyms: 4-(4-aminophenylsulfonyl)aniline, p,p-sulphonylbisbenzamineMixtures: Dapsone 6% / Niacinamide 2% / Spironolactone 5%, 011503 Dapsone 6% / Niacinamide 2% / Spironolactone 5%