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Displaying results 5421 - 5430 of 10000 in total
  1. Target

    5-hydroxytryptamine receptor 1D

    go.drugbank.com/bio_entities/BE0000659
    TargetHumans

    G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:10452531, PubMed:1565658, PubMed:1652050, PubMed:33762731). … Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity (PubMed:18476671, PubMed:20945968).

    Polypeptides: 5-hydroxytryptamine receptor 1DSynonyms: 5-HT-1D, 5-HT1D
  2. Target

    Metabotropic glutamate receptor 5

    go.drugbank.com/bio_entities/BE0001192
    TargetHumans

    G protein-coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a...

    Polypeptides: Metabotropic glutamate receptor 5
  3. Target

    5-hydroxytryptamine receptor 5A

    go.drugbank.com/bio_entities/BE0004688
    TargetHumans

    G protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:35610220, PubMed:35835867, PubMed:9865521). … proteins and mediates inhibitory neurotransmission: signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+

    Polypeptides: 5-hydroxytryptamine receptor 5ASynonyms: 5-HT-5, 5-HT5A
  4. Target

    5-hydroxytryptamine receptor 2C

    go.drugbank.com/bio_entities/BE0004882
    TargetRat

    G-protein coupled receptor for 5-hydroxytryptamine (serotonin). … Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD)

    Polypeptides: 5-hydroxytryptamine receptor 2CSynonyms: 5-HT1C, 5-HT-1C
  5. Target

    Chromobox protein homolog 5

    go.drugbank.com/bio_entities/BE0009056
    TargetHumans

    Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression (PubMed:40440427). In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phospho...

    Polypeptides: Chromobox protein homolog 5
  6. Target

    Serine repeat antigen 5

    go.drugbank.com/bio_entities/BE0009196
    TargetPlasmodium falciparum

    Polypeptides: Serine repeat antigen 5
  7. Target

    5-hydroxytryptamine receptor 3D

    go.drugbank.com/bio_entities/BE0009585
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3DSynonyms: 5-HT3D, 5-HT3-D
  8. Drug

    Bemiparin

    go.drugbank.com/drugs/DB09258
    ApprovedInvestigationalWithdrawn

    Like semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class [A7866]. … These heparins have lower anti-thrombin activity than the traditional low molecular weight heparins and act mainly on factor-Xa, reducing the risk of bleeding due to selectivity for this specific clotting

    Products: HIBOR 2500 IU/0,2 ML KULLANIMA HAZIR 2 ENJEKTOR, HIBOR 5000 IU/0,2 ML SC KULLANIMA HAZIR ENJEKTÖR, 2 ADET
  9. Drug

    Oxygen

    go.drugbank.com/drugs/DB09140
    ApprovedInvestigationalVet approved

    Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. … Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow resistance in the diseased lung, leading to decreased cardiovascular workload in

    Mixtures: OXICALM® MEZCLA MEDICINAL DE OXIGENO: OXIDO NITROSO, Co-NE-O2-N2 MixtureProducts: Oxygen Size D, Oxygen Size M
  10. Drug

    Nirsevimab

    go.drugbank.com/drugs/DB16258
    ApprovedInvestigational

    [A254691] This is due to a modification in the Fc region of nirsevimab that grants it a longer half-time compared to typical monoclonal antibodies. … [L44146] It binds to the prefusion conformation of the RSV F protein, a glycoprotein involved in the membrane fusion step of the viral entry process, and neutralizes several RSV A and B strains.

    Categories: Respiratory Syncytial Virus Anti-F Protein Monoclonal AntibodySynonyms: Immunoglobulin g1-kappa, anti-(human respiratory syncytial virus fusion glycoprotein f0 (protein f))human monoclonal antibody.gamma.1 heavy chain (1-456) (human vh (homo sapiens ighv1-69*01(ighd)-ighj4, *01 (90.1%)) (8.8.19) (1-126) -homo sapiens ighg1*03