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Displaying results 5421 - 5430 of 10000 in total
  1. Target

    5-hydroxytryptamine receptor 2A

    go.drugbank.com/bio_entities/BE0000451
    TargetHumans

    G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:1330647, PubMed:18703043, PubMed:19057895, PubMed:21645528, PubMed:22300836, PubMed:35084960, PubMed:38552625). … Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD) (PubMed

    Polypeptides: 5-hydroxytryptamine receptor 2ASynonyms: 5-HT-2, 5-HT-2A
  2. Target

    5-hydroxytryptamine receptor 1D

    go.drugbank.com/bio_entities/BE0000659
    TargetHumans

    G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:10452531, PubMed:1565658, PubMed:1652050, PubMed:33762731). … Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity (PubMed:18476671, PubMed:20945968).

    Polypeptides: 5-hydroxytryptamine receptor 1DSynonyms: 5-HT-1D, 5-HT1D
  3. Target

    Metabotropic glutamate receptor 5

    go.drugbank.com/bio_entities/BE0001192
    TargetHumans

    G protein-coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a...

    Polypeptides: Metabotropic glutamate receptor 5
  4. Target

    5-hydroxytryptamine receptor 5A

    go.drugbank.com/bio_entities/BE0004688
    TargetHumans

    G protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:35610220, PubMed:35835867, PubMed:9865521). … proteins and mediates inhibitory neurotransmission: signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+

    Polypeptides: 5-hydroxytryptamine receptor 5ASynonyms: 5-HT-5, 5-HT5A
  5. Target

    5-hydroxytryptamine receptor 2C

    go.drugbank.com/bio_entities/BE0004882
    TargetRat

    G-protein coupled receptor for 5-hydroxytryptamine (serotonin). … Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD)

    Polypeptides: 5-hydroxytryptamine receptor 2CSynonyms: 5-HT1C, 5-HT-1C
  6. Target

    Chromobox protein homolog 5

    go.drugbank.com/bio_entities/BE0009056
    TargetHumans

    Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression (PubMed:40440427). In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phospho...

    Polypeptides: Chromobox protein homolog 5
  7. Target

    Serine repeat antigen 5

    go.drugbank.com/bio_entities/BE0009196
    TargetPlasmodium falciparum

    Polypeptides: Serine repeat antigen 5
  8. Target

    5-hydroxytryptamine receptor 3D

    go.drugbank.com/bio_entities/BE0009585
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3DSynonyms: 5-HT3D, 5-HT3-D
  9. Drug

    Lixisenatide

    go.drugbank.com/drugs/DB09265
    ApprovedInvestigational

    Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). … It is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU.[L764] Adlyxin recieved FDA approval July 28, 2016.[L763]

    Mixtures: SOLİQUA SOLOSTAR 100 U/ML + 50 MCG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 KALEM, SOLİQUA SOLOSTAR 100 U/ML + 33 MCG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 KALEMCategories: Receptors, G-Protein-Coupled, Glucagon-like peptide-1 (GLP-1) analogues
  10. Drug

    Permethrin

    go.drugbank.com/drugs/DB04930
    ApprovedInvestigational

    A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.

    Synonyms: (3-Phenoxyphenyl)methyl (±)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate, 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropane carboxylic acid, (3-phenoxyphenyl) methyl esterCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Inducers