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Displaying results 5481 - 5490 of 10000 in total
  1. Drug

    Deupirfenidone

    go.drugbank.com/drugs/DB19056
    Investigational

    Deupirfenidone is under investigation in clinical trial NCT05321420 (LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)).

    Synonyms: 2(1h)-pyridinone, 5-(methyl-d3)-1-phenyl-, 1-phenyl-5-(trideuteriomethyl)-1,2-dihydropyridin-2-oneCategories: Heterocyclic Compounds, 1-Ring
  2. Drug

    NV-5138

    go.drugbank.com/drugs/DB19180
    Investigational

    NV-5138 is under investigation in clinical trial NCT06235905 (Open-label of SPN-820 in Adults With Major Depressive Disorder).

    Synonyms: ((S)-2-AMINO-5,5-DIFLUORO-4,4-DIMETHYLPENTANOIC ACID, Pentanoic acid, 2-amino-5,5-difluoro-4,4-dimethyl-, (2s)-
  3. Drug

    Nepicastat

    go.drugbank.com/drugs/DB12979
    Investigational

    Nepicastat has been investigated for the treatment of Cocaine Dependence and Posttraumatic Stress Disorder.

    Synonyms: (S)-5-aminomethyl-1-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)-1,3-dihydroimidazole-2-thioneCategories: P-glycoprotein substrates, Heterocyclic Compounds, 1-Ring
  4. Drug

    Denatonium

    go.drugbank.com/drugs/DB18588
    Investigational

    Synonyms: Benzenemethanaminium, n-(2-((2,6-dimethylphenyl)amino)-2-oxoethyl)-n,n-diethylCategories: Compounds used in a research, industrial, or household setting
  5. Drug

    Docetaxel

    go.drugbank.com/drugs/DB01248
    ApprovedInvestigational

    Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel]. … [A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and promote to cell death.

    Synonyms: N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol, N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxelCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  6. Drug

    N,N-[2,5-O-Dibenzyl-glucaryl]-DI-[1-amino-indan-2-OL]

    go.drugbank.com/drugs/DB01887
    Experimental

    Synonyms: N,N-[2,5-O-Dibenzyl-glucaryl]-DI-[1-amino-indan-2-OL]
  7. Drug

    Corticosterone

    go.drugbank.com/drugs/DB04652
    Investigational

    An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. … (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 11beta,21-Dihydroxy-4-pregnene-3,20-dione, (11β)-11,21-dihydroxypregn-4-ene-3,20-dione
  8. Drug

    Alemtuzumab

    go.drugbank.com/drugs/DB00087
    ApprovedInvestigational

    [L43397] It is marketed as LEMTRADA for multiple sclerosis (MS) treatment and CAMPTAH for B-cell chronic lymphocytic leukemia (B-CLL). … The dose of alemtuzumab used for B-CLL is much higher than that for MS, and also at more frequent dosing.[L43397, L30335]

    Synonyms: Campath 1-HProducts: MABCAMPATH INF SOL ICIN 30 MG/ML KONS 1 ML 3 FLK (10 MG/ML KONSANTRE 3 AMP), MABCAMPATH ® 30 MG/ML
  9. Drug

    Hyaluronic acid

    go.drugbank.com/drugs/DB08818
    ApprovedInvestigationalVet approved

    A popular use of hyaluronic acid in recent years is cosmetic injection due to its ability to minimize the appearance of wrinkles and aging-related skin imperfections.[L32193]

    Mixtures: Calcipotriene 0.005% / Diclofenac Sodium 3% / Hyaluronic Acid Sodium Salt 2% / Niacinamide 2%, Hyaluronic Acid Sodium Salt 2% / Mometasone Furoate 0.1% / Niacinamide 4%Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Becatecarin

    go.drugbank.com/drugs/DB06362
    Investigational

    Becatecarin is a derivative of [rebeccamycin].

    Synonyms: 6-(2-(DIETHYLAMINO)ETHYL)-REBECCAMYCINCategories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 3-Ring