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Displaying results 541 - 550 of 10000 in total
  1. Target

    Glutathione S-transferase

    go.drugbank.com/bio_entities/BE0004124
    TargetBurkholderia xenovorans (strain LB400)

    Polypeptides: Glutathione S-transferaseSynonyms: Glutathione S-transferase (BphK)
  2. Target

    S-adenosylmethionine synthase

    go.drugbank.com/bio_entities/BE0009188
    TargetPlasmodium falciparum (isolate 3D7)

    Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

    Polypeptides: S-adenosylmethionine synthase
  3. Target

    Thiopurine S-methyltransferase

    go.drugbank.com/bio_entities/BE0000987
    EnzymeTargetHumans

    Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) and 6-thioguanine (also called tioguanine or 6-TG) using S-adenosyl-L-methionine

    Polypeptides: Thiopurine S-methyltransferaseFunction: S-adenosyl-L-methionine binding
  4. Target

    S-ribosylhomocysteine lyase

    go.drugbank.com/bio_entities/BE0001497
    TargetBacillus subtilis (strain 168)

    Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

    Polypeptides: S-ribosylhomocysteine lyase
  5. Target

    S-adenosylmethionine synthase

    go.drugbank.com/bio_entities/BE0001499
    TargetShigella flexneri

    Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.

    Polypeptides: S-adenosylmethionine synthase
  6. Target

    Glutathione S-transferase

    go.drugbank.com/bio_entities/BE0002659
    TargetEnzymePlasmodium falciparum

    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May also function as a storage protein or ligandin for parasitotoxic ferriprotoporphyrin IX (hemin).

    Polypeptides: Glutathione S-transferase
  7. Drug

    Betaxolol

    go.drugbank.com/drugs/DB00195
    ApprovedInvestigational

    A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.

    Categories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor AntagonistsSynonyms: 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol, 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol
  8. Drug

    Clofibrate

    go.drugbank.com/drugs/DB00636
    ApprovedWithdrawn

    A fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: 2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester, 2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl ester
  9. Drug

    Sulfamethizole

    go.drugbank.com/drugs/DB00576
    ApprovedVet approved

    A sulfathiazole antibacterial agent.

    Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: S*ORIPOL FORTE®., S- URISTIX 500 MG CAPSULAS
  10. Indication

    Insufficient response to Betoptic-S

    go.drugbank.com/conditions/DBCOND0106067
    Drugs: Betaxolol
    Synonyms: Insufficient response to Betoptic-S