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Tucatinib
go.drugbank.com/drugs/DB11652ApprovedInvestigationalTucatinib is a kinase inhibitor drug used with [trastuzumab] and [capecitabine] in the treatment of unresectable or metastatic HER-2 positive breast cancer. … [L12951] Tucatinib is a promising new treatment for patients with metastatic breast cancer who have not responded adequately to other chemotherapy regimens.[L12945]
Categories: MATE 2 Inhibitors, Heterocyclic Compounds, 2-RingProducts: TUKYSA 50 mg film-coated tablets, TUKYSA 150 mg film-coated tabletsFedratinib
go.drugbank.com/drugs/DB12500ApprovedInvestigationalFedratinib, also known as SAR302503 and TG101348, is a tyrosine kinase inhibitor used to treat intermediate-2 and high risk primary and secondary myelofibrosis.
Categories: MATE 2 Inhibitors, MATE 1 InhibitorsProducts: Inrebic 100 mg capsules, Inrebic 100 mg Sert Kapsül, 120 ADETTropisetron
go.drugbank.com/drugs/DB11699ApprovedInvestigationalWithdrawnAs a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: NAVOBAN 5 MG 1 AMPUL, Navoban 5 mg - KapselnAmitriptyline
go.drugbank.com/drugs/DB00321ApprovedInvestigationalAmitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961.
Synonyms: 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amineMixtures: Apo Peram Tab 2-25, PMS-levazine 2/25 TabMethylprednisolone aceponate
go.drugbank.com/drugs/DB14643ApprovedVet approvedProducts: Skinatan 1 mg/ml Lösung zur Anwendung auf der Haut, Methylprednisolonaceponat GALEN Lotion 1 mg/g Emulsion zur Anwendung auf der HautPramipexole
go.drugbank.com/drugs/DB00413ApprovedInvestigationalPramipexole is a drug used to treat the symptoms of Parkinson's Disease (PD). … It is a _non-ergot dopamine agonist_ drug that is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement) [A176867].
Synonyms: (S)-N 6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamineCategories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-RingErythema Nodosum Leprosum
go.drugbank.com/conditions/DBCOND0036567Drugs: ThalidomideSynonyms: Type 2 lepra reactionIsosorbide dinitrate
go.drugbank.com/drugs/DB00883ApprovedInvestigationalA vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.
Synonyms: D-Isosorbide dinitrateCategories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 Enzyme InhibitorsTyphoid Vi polysaccharide vaccine
go.drugbank.com/drugs/DB10803ApprovedInvestigationalTyphoid Vi polysaccharide vaccine is a vaccine that is administered intramuscularly. … The vaccine contains the purified cell surface Vi polysaccharide extracted from *Salmonella enterica* serovar *Typhi, S typhi Ty2* strain.
Synonyms: Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strainProducts: TYPHIM VI INJECTION 0.025 mg/0.5 ml, TYPHIM VI 0,5 ML IM/SC ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETSunitinib
go.drugbank.com/drugs/DB01268ApprovedInvestigationalThese include all platelet-derived growth factor receptors (PDGF-R) and vascular endothelial growth factor receptors (VEGF-R). … Sunitinib is a small-molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: SUTENT® CAPSULAS 25 MG, RENISUN® 25 MG CAPSULAS