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S-adenosylmethionine decarboxylase proenzyme
go.drugbank.com/bio_entities/BE0000101TargetHumansEssential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels
Polypeptides: S-adenosylmethionine decarboxylase proenzyme(S)-2-haloacid dehalogenase
go.drugbank.com/bio_entities/BE0001647TargetPseudomonas sp. (strain YL)Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids (PubMed:7490277, PubMed:9614112). … Active with 2-halogenated carboxylic acids and converts only the S-isomer (or L-isomer) of 2-chloropropionic acid with inversion of configuration to produce R-lactate (or D-isomer) (PubMed:7490277, PubMed
Polypeptides: (S)-2-haloacid dehalogenaseFunction: (S)-2-haloacid dehalogenase activityGlutathione S-transferase GstA
go.drugbank.com/bio_entities/BE0002062TargetEscherichia coli (strain K12)Catalyzes the conjugation of reduced glutathione (GSH) to a wide number of exogenous and endogenous hydrophobic electrophiles. Shows activity toward 1-chloro-2,4-dinitrobenzene (CDNB) and ethacrynic acid. Also possesses thiol:disulfide o...
Polypeptides: Glutathione S-transferase GstAGlutathione S-transferase A1
go.drugbank.com/bio_entities/BE0002281TargetEnzymeHumansGlutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable).
Polypeptides: Glutathione S-transferase A1Glutathione S-transferases (Cytosolic)
go.drugbank.com/bio_entities/BE0010006TargetEnzymeHumansCan also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator … Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable).
Polypeptides: Glutathione S-transferase A1, Glutathione S-transferase A2Synonyms: Glutathione S-transferase, Glutathione S-transferase theta-2European pilchard
go.drugbank.com/drugs/DB10622ApprovedEuropean pilchard allergenic extract is used in allergenic testing.
Synonyms: European pilchardElenestinib
go.drugbank.com/drugs/DB18489InvestigationalElenestinib is a selective KIT inhibitor.
Synonyms: (S)-2-(4-(4-(4-(5-(1-amino-1-(4-fluorophenyl)ethyl)pyrimidin-2-yl)piperazin-1-yl)pyrrolo[2,1-f][1,2,4]triazin-6-yl)-1H-pyrazol-1-yl)ethan-1-ol, 1H-Pyrazole-1-ethanol, 4-[4-[4-[5-[(1S)-1-amino-1-(4-fluorophenyl)ethyl]-2-pyrimidinyl]-1-piperazinyl]pyrrolo[2,1-f][1,2,4]triazin-6-yl]-Severe, active Crohn´s Disease
go.drugbank.com/conditions/DBCOND0123591Synonyms: Severe, active Crohn´s DiseaseDexketoprofen
go.drugbank.com/drugs/DB09214ApprovedInvestigationalWithdrawnDexketoprofen is a non-steroidal anti-inflammatory drug. It is available in the various countries in Europe, Asia and Latin America.
Mixtures: Skudexa 75 mg/25 mg Granulat im Beutel zur Herstellung einer Lösung zum Einnehmen, INDEXPA SR 75/300MG FILM KAPLI TABLET, 10 SR FILM KAPLI TABLETCategories: Non COX-2 selective NSAIDSGlutathione S-transferase Mu 1
go.drugbank.com/bio_entities/BE0000807TargetEnzymeHumansConjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911). ...
Polypeptides: Glutathione S-transferase Mu 1