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Displaying results 551 - 560 of 10000 in total
  1. Target

    Glutathione S-transferase GstA

    go.drugbank.com/bio_entities/BE0002062
    TargetEscherichia coli (strain K12)

    Catalyzes the conjugation of reduced glutathione (GSH) to a wide number of exogenous and endogenous hydrophobic electrophiles. Shows activity toward 1-chloro-2,4-dinitrobenzene (CDNB) and ethacrynic acid. Also possesses thiol:disulfide o...

    Polypeptides: Glutathione S-transferase GstA
  2. Target

    Glutathione S-transferase A1

    go.drugbank.com/bio_entities/BE0002281
    TargetEnzymeHumans

    Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable).

    Polypeptides: Glutathione S-transferase A1
  3. Target

    Glutathione S-transferases (Cytosolic)

    go.drugbank.com/bio_entities/BE0010006
    TargetEnzymeHumans

    Can also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator … Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable).

    Polypeptides: Glutathione S-transferase A1, Glutathione S-transferase A2Synonyms: Glutathione S-transferase, Glutathione S-transferase theta-2
  4. Drug

    European pilchard

    go.drugbank.com/drugs/DB10622
    Approved

    European pilchard allergenic extract is used in allergenic testing.

    Synonyms: European pilchard
  5. Drug

    Elenestinib

    go.drugbank.com/drugs/DB18489
    Investigational

    Elenestinib is a selective KIT inhibitor.

    Synonyms: (S)-2-(4-(4-(4-(5-(1-amino-1-(4-fluorophenyl)ethyl)pyrimidin-2-yl)piperazin-1-yl)pyrrolo[2,1-f][1,2,4]triazin-6-yl)-1H-pyrazol-1-yl)ethan-1-ol, 1H-Pyrazole-1-ethanol, 4-[4-[4-[5-[(1S)-1-amino-1-(4-fluorophenyl)ethyl]-2-pyrimidinyl]-1-piperazinyl]pyrrolo[2,1-f][1,2,4]triazin-6-yl]-
  6. Indication

    Severe, active Crohn´s Disease

    go.drugbank.com/conditions/DBCOND0123591
    Drugs: Guselkumab · Risankizumab · Upadacitinib · Ustekinumab
    Synonyms: Severe, active Crohn´s Disease
  7. Drug

    Dexketoprofen

    go.drugbank.com/drugs/DB09214
    ApprovedInvestigationalWithdrawn

    Dexketoprofen is a non-steroidal anti-inflammatory drug. It is available in the various countries in Europe, Asia and Latin America.

    Mixtures: Skudexa 75 mg/25 mg Granulat im Beutel zur Herstellung einer Lösung zum Einnehmen, INDEXPA SR 75/300MG FILM KAPLI TABLET, 10 SR FILM KAPLI TABLETCategories: Non COX-2 selective NSAIDS
  8. Target

    Glutathione S-transferase Mu 1

    go.drugbank.com/bio_entities/BE0000807
    TargetEnzymeHumans

    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911). ...

    Polypeptides: Glutathione S-transferase Mu 1
  9. Target

    Glutathione S-transferase theta-1

    go.drugbank.com/bio_entities/BE0000818
    TargetEnzymeHumans

    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays...

    Polypeptides: Glutathione S-transferase theta-1
  10. Target

    G1/S-specific cyclin-D1

    go.drugbank.com/bio_entities/BE0001027
    TargetHumans

    Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition

    Polypeptides: G1/S-specific cyclin-D1