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Lormetazepam
go.drugbank.com/drugs/DB13872ApprovedLormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia [L927]. … It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.
Synonyms: (RS)-LormetazepamEthinamate
go.drugbank.com/drugs/DB01031ApprovedIllicitWithdrawnLike many such similar medications, the regular use of ethinamate can result in the development of drug tolerance in a patient. … Ethinamate is a short-acting sedative-hypnotic medication used to treat insomnia.
Podofilox
go.drugbank.com/drugs/DB01179ApprovedIt is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. … It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives
Peptide YY (3-36)
go.drugbank.com/drugs/DB05004InvestigationalPeptide YY (3-36), a synthetic human PYY 3-36, is a compound being evaluated for the treatment of obesity. It reduces appetite and increases satiety in obese patients.
Tropisetron
go.drugbank.com/drugs/DB11699ApprovedInvestigationalWithdrawnTropisetron is an indole derivative with antiemetic activity. … As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting
SGS-742
go.drugbank.com/drugs/DB05010InvestigationalSGS-742 has been used in trials studying the treatment of Seizures and Metabolic Disease.
Mephentermine
go.drugbank.com/drugs/DB01365ApprovedWithdrawnAlthough the central stimulant effects of mephentermine are much less than those of amphetamine, its use may lead to amphetamine-type dependence. … It is used to maintain blood pressure in hypotensive states, for example, following spinal anesthesia.
Resiniferatoxin
go.drugbank.com/drugs/DB06515InvestigationalResiniferatoxin (RTX) is a naturally occurring, ultrapotent capsaicin analog that activates the vanilloid receptor in a subpopulation of primary afferent sensory neurons involved in nociception (the transmission
YKP-1358
go.drugbank.com/drugs/DB06109ExperimentalYKP1358 is a novel serotonin (5-HT2A) and dopamine (D2) antagonist that has demonstrated potent activity in animals that relates to both positive and negative symptoms of schizophrenia.