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Displaying results 5651 - 5660 of 10000 in total
  1. Drug

    Pentazocine

    go.drugbank.com/drugs/DB00652
    ApprovedVet approved

    The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor.

    Categories: P-glycoprotein substratesProducts: Pentazocine-Fresenius 30 mg/ml injection, Talwin - Liq 30mg/ml
  2. Drug

    Ersodetug

    go.drugbank.com/drugs/DB18182
    Investigational

    Synonyms: (119-216), hinge 1-12 (217-228), CH2 M45.1 (279) (2, gamma2 heavy chain Homo sapiens (1-444) [VH(Homo sapiens IGHV3-20*01 (98.0%) -(IGHD)-IGHJ6*01 (93.8%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG2*02 (100%), G2m23 CH2 M45.1 (CH1
  3. Drug

    Sabestomig

    go.drugbank.com/drugs/DB19326
    Investigational

    Sabestomig is under investigation in clinical trial NCT05216835 (Safety and Preliminary Efficacy Assessment of AZD7789 in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma).

    Synonyms: Immunoglobulin G1-kappa/lambda, anti-[Homo sapiens PDCD1 (programmed cell death 1, PD1, PD-1, CD279) and HAVCR2 (hepatitis A virus cellular receptor 2, T cell immunoglobulin and mucin domains family member, 3, TIM3, TIM-3, TIMD3, CD366)], humanized and Ho
  4. Drug

    Gadobenic acid

    go.drugbank.com/drugs/DB00743
    ApprovedInvestigational

    Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. … [A263086] It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity.

    Mixtures: MULTIHANCE INJECTION 10 ML, MULTIHANCE INJECTION 10 MLCategories: Compounds used in a research, industrial, or household setting
  5. Pathway

    Acylcarnitine 5-(3,4-dimethyl-5-pentylfuran-2-yl)pentanoylcarnitine

    smpdb.ca/view/SMP0123510
    Metabolic

    5-(3,4-dimethyl-5-pentylfuran-2-yl)pentanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-(3,4-dimethyl-5-pentylfuran-2-yl)pentanoyl-CoA reacts with L-carnitine to form 5-(3,4-dimethyl-5-pentylfuran-2-yl)pentanoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5, Carnitine O-palmitoyltransferase 2, mitochondrial
  6. Drug

    Sodium phosphate, monobasic

    go.drugbank.com/drugs/DB09449
    ApprovedInvestigational

    Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.

    Mixtures: AMINOPLASMAL-5% E INFUSION, Urin D/SProducts: BT ORAL SOLUSYON 45 ML, SODIO FOSFATO LJ PHARMA
  7. Pathway

    Acylcarnitine 5-(3-methyl-5-pentylfuran-2-yl)pentanoylcarnitine

    smpdb.ca/view/SMP0123511
    Metabolic

    5-(3-methyl-5-pentylfuran-2-yl)pentanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-(3-methyl-5-pentylfuran-2-yl)pentanoyl-CoA reacts with L-carnitine to form 5-(3-methyl-5-pentylfuran-2-yl)pentanoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5, Carnitine O-palmitoyltransferase 2, mitochondrial
  8. Target

    Interleukin-2

    go.drugbank.com/bio_entities/BE0001029
    TargetHumans

    Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance (PubMed:6438535). Binds to a rec...

    Polypeptides: Interleukin-2Synonyms: IL-2
  9. Target

    Carboxylesterase 2

    go.drugbank.com/bio_entities/BE0003048
    TargetPseudomonas fluorescens

    Hydrolyzes carboxylic ester bonds with relatively broad substrate specificity.

    Polypeptides: Carboxylesterase 2
  10. Target

    Sialidase-2

    go.drugbank.com/bio_entities/BE0003200
    TargetHumans

    Cleaves milk oligosaccharide alpha-(2->3)-sialyllactose, but is inactive toward alpha-(2->6)-sialyllactose isomer. … Displays preference for alpha-(2->3)-sialylated GD1a and GT1B gangliosides over alpha-(2->8)-sialylated GD1b, in both monomeric forms and micelles.

    Polypeptides: Sialidase-2Synonyms: Neuraminidase-2, N-acetyl-alpha-neuraminidase 2