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cAMP-dependent protein kinase (Protein kinase A)
go.drugbank.com/bio_entities/BE0010127TargetHumansPhosphorylates a large number of substrates in the cytoplasm and the nucleus … Acts as a negative regulator of mTORC1 by mediating phosphorylation of RPTOR (PubMed:31112131)
House dust
go.drugbank.com/drugs/DB10345ApprovedHouse dust allergenic extract is used in allergenic testing.
Products: A. Dust, Center-AL - House DustV-type proton ATPase catalytic subunit A
go.drugbank.com/bio_entities/BE0003569TargetHumansCatalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates … V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it promotes acidification of the extracellular
Polypeptides: V-type proton ATPase catalytic subunit ASynonyms: V-ATPase subunit ANuclear receptor subfamily 4immunitygroup A member 1
go.drugbank.com/bio_entities/BE0010494TargetHumansPlays a role in the vascular response to injury (By similarity) … Inhibits NF-kappa-B signaling by binding to low-affinity NF-kappa-B binding sites, such as at the IL2 promoter (PubMed:15466594).
Polypeptides: Nuclear receptor subfamily 4immunitygroup A member 1Inositol polyphosphate-4-phosphatase type I A
go.drugbank.com/bio_entities/BE0018619EnzymeHumansCatalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) (PubMed:15716355, PubMed:20463662). Also catalyzes inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate (By similarity). ...
Polypeptides: Inositol polyphosphate-4-phosphatase type I AAmlodipine
go.drugbank.com/drugs/DB00381ApprovedInvestigationalDue to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities than … Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called _dihydropyridine calcium channel blockers_.
Synonyms: (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate, 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylateInternational brands: Atecard-AM, Amlodipine 5Methoxsalen
go.drugbank.com/drugs/DB00553ApprovedInvestigationalIt is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation. … A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia.
Synonyms: 6-hydroxy-7-methoxy-5-benzofuranacrylic acid δ-lactone, 9-methoxy-7H-furo[3,2-g][1]benzopyran-7-oneCategories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingCetylpyridinium
go.drugbank.com/drugs/DB11073ApprovedInvestigationalCetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. … Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays.
Synonyms: 1-hexadecylpyridiniumMixtures: Kank-A, NORAVER P TABLETAS DE DISOLUCIÓN BUCALVascular endothelial growth factor A, long form
go.drugbank.com/bio_entities/BE0000163TargetHumansParticipates in the induction of key genes involved in the response to hypoxia and in the induction of angiogenesis such as HIF1A (PubMed:35455969). Involved in protecting cells from hypoxia-mediated cell death (By similarity)
Polypeptides: Vascular endothelial growth factor A, long form3-hydroxy-3-methylglutaryl-coenzyme A reductase
go.drugbank.com/bio_entities/BE0001856TargetPseudomonas mevaloniiP.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.
Polypeptides: 3-hydroxy-3-methylglutaryl-coenzyme A reductase