Search

Displaying results 5711 - 5720 of 8694 in total
  1. Target

    CD44 antigen

    go.drugbank.com/bio_entities/BE0001113
    TargetHumans

    Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment (PubMed:16541107, PubMed:19703720 … components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor

    Synonyms: Hyaluronate receptor, Extracellular matrix receptor IIIFunction: cargo receptor activity
  2. Target

    Small ribosomal subunit protein uS2

    go.drugbank.com/bio_entities/BE0002402
    TargetHumans

    May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA … Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways.

    Synonyms: Laminin receptor 1, 67 kDa laminin receptor
  3. Drug

    Benzoylecgonine

    go.drugbank.com/drugs/DB01515
    ExperimentalIllicit

    It is the main pharmaceutical ingredient in the investigational drug Esterom, a topical solution used for the relief of muscle pain that is not FDA approved or on the market in the United States.

  4. Drug

    Octacosanol

    go.drugbank.com/drugs/DB11220
    InvestigationalNutraceutical

    This high–molecular-weight organic compound is the main component of a natural product wax extracted from plants [A27245]. 1-octacosanol is reported to possess cholesterol-lowering effects, antiaggregatory … It has been studied as a potential therapeutic agent for the treatment of Parkinson's disease.

  5. Drug

    Gluconolactone

    go.drugbank.com/drugs/DB04564
    Approved

    Gluconolactone is a naturally-occurring food additive used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent. It is a cyclic ester of D-gluconic acid.

  6. Drug

    Phenprocoumon

    go.drugbank.com/drugs/DB00946
    ApprovedInvestigationalWithdrawn

    Coumarin derivative that acts as a long-acting oral anticoagulant.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Substrates
  7. Drug

    Methane

    go.drugbank.com/drugs/DB15994
    Investigational

    Mixtures: iCOmas 0,3 % / 0,3 % / 0,3 % Gas zur medizinischen Anwendung, druckverdichtet
  8. Drug

    ReN001

    go.drugbank.com/drugs/DB05236
    Investigational

    ReN001 a strong candidate for one of the first cell-based IND applications to be submitted to the Food and Drug Administration in the United States for consideration for the treatment of stroke in humans … ReN001 is a clonal human neural stem cell line developed for clinical use in the treatment of stable disability after stroke.

  9. Drug

    Thyroglobulin

    go.drugbank.com/drugs/DB01584
    ApprovedWithdrawn

    Thyroglobulin (also known as Tg) is an enzyme thyroid hormone used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3).

  10. Drug

    OTL-201

    go.drugbank.com/drugs/DB17652
    Experimental

    OTL-201 is an investigational hematopoietic stem cell (HSC) gene therapy being developed by Orchard Therapeutics for the treatment of mucopolysaccharidosis type IIIA (MPS-IIIA).