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Displaying results 5721 - 5730 of 10000 in total
  1. Drug

    Mirabegron

    go.drugbank.com/drugs/DB08893
    ApprovedInvestigational

    Mirabegron is a sympathomimetic beta-3 adrenergic receptor agonist used to relax the smooth muscle of the bladder in the treatment of urinary frequency and incontinence. … Mirabegron has a comparatively favorable adverse effect profile as compared to other available treatment options, and its complementary mechanism to the antimuscarinics that came before it allows for its

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: MYRBETRIC® 25 MG TABLETAS DE LIBERACION PROLONGADA, MYRBETRIC® 50 MG TABLETAS DE LIBERACION PROLONGADA
  2. Drug

    Deferiprone

    go.drugbank.com/drugs/DB08826
    ApprovedInvestigational

    Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired. … Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 1,2-Dimethyl-3-hydroxypyrid-4-one, 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone
  3. Drug

    Technetium Tc-99m pertechnetate

    go.drugbank.com/drugs/DB09314
    ApprovedInvestigational

    This is normally supplied in a hospital setting through the use of a technetium-99m generator, whereby technetium exits the generator in the form of the pertechnetate ion, TcO4−, which can be extracted … Pertechnetate has a wide variety of uses within nuclear medicine as it distributes within the body to a similar extent as iodine.

    Mixtures: GENERADOR DE SOLUCION INYECTABLE DE PERTECNETATO (99MTC) DE SODIO. 2-50GBQ, POLGENTEC 2-120 GBQ GENERADOR DE RADIONUCLEIDOSCategories: Compounds used in a research, industrial, or household setting
  4. Drug

    Atazanavir

    go.drugbank.com/drugs/DB01072
    ApprovedInvestigational

    Food and Drug Administration (FDA) approved atazanavir on June 20, 2003. … Atazanavir is distinguished from other PIs in that it can be given once daily (rather than requiring multiple doses per day) and has lesser effects on the patient's lipid profile (the amounts of cholesterol

    Mixtures: ANCEF ® R, ANCEF ® RCategories: P-glycoprotein inducers, P-glycoprotein inhibitors
  5. Indication

    Lupus Erythematosus

    go.drugbank.com/conditions/DBCOND0029690
    Drugs: Betamethasone · Tetracosactide
    Synonyms: LE syndrome, LE systemic
  6. Drug

    Bacillus clausii

    go.drugbank.com/drugs/DB16537
    Investigational

    Synonyms: B. clausiiProducts: Enterogermina 2 Billions/5 ml oral suspension, Enterogermina 2 Billions hard capsules
  7. Pathway

    Acylcarnitine (2Z)-5-Hydroxydec-2-enedioylcarnitine

    smpdb.ca/view/SMP0123884
    Metabolic

    (2Z)-5-Hydroxydec-2-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (2Z)-5-hydroxydec-2-enedioyl-CoA reacts with L-carnitine to form (2Z)-5-hydroxydec-2-enedioylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5, Carnitine O-palmitoyltransferase 2, mitochondrial
  8. Target

    Gamma-aminobutyric acid receptor subunit alpha-5

    go.drugbank.com/bio_entities/BE0000471
    TargetHumans

    Extrasynaptic alpha-5-containing GABAARs in CA1 pyramidal neurons play a role in learning and memory processes (By similarity) … GABAARs containing alpha-5/GABRA5 subunits are mainly extrasynaptic and contribute to the tonic GABAergic inhibition in the hippocampus (By similarity).

    Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-5Synonyms: GABAAR subunit alpha-5, GABA(A) receptor subunit alpha-5
  9. Target

    1-deoxy-D-xylulose 5-phosphate reductoisomerase

    go.drugbank.com/bio_entities/BE0001575
    TargetEscherichia coli (strain K12)

    Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

    Polypeptides: 1-deoxy-D-xylulose 5-phosphate reductoisomeraseSynonyms: 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase
  10. Target

    T cell receptor beta variable 6-5

    go.drugbank.com/bio_entities/BE0021562
    TargetHumans

    V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and ...

    Polypeptides: T cell receptor beta variable 6-5