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Clonidine
go.drugbank.com/drugs/DB00575ApprovedInvestigationalClonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors.[A180559] This activity is useful for the treatment of hypertension, severe pain, and ADHD. … [L7237,L54536,L7240,L7243,L7246] Clonidine was granted FDA approval on 3 September 1974.[L7237]
Categories: Sympathomimetics in Glaucoma Therapy, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: 2,6-Dichloro-N-2-imidazolidinylidenebenzenamine, 2-((2,6-Dichlorophenyl)imino)imidazolidineEstradiol valerate
go.drugbank.com/drugs/DB13956ApprovedInvestigationalVet approvedHowever, after menopause, most endogenous estrogen is produced by conversion of androstenedione, secreted by the adrenal cortex, to estrone by peripheral tissues. … [DB00783] is commonly produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2-10%).
Mixtures: CYCLO PROGYNOVA N 2MG/0.15, CYCLO PROGYNOVA N 2MG/0.15Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesChromic chloride
go.drugbank.com/drugs/DB09129ApprovedChromic chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).
Mixtures: Addamel N, ADDAMEL NCategories: Compounds used in a research, industrial, or household settingLevonorgestrel
go.drugbank.com/drugs/DB00367ApprovedInvestigationalto older emergency contraceptive regimens. … [A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD.
Mixtures: CYCLO PROGYNOVA N 2MG/0.15, CYCLO PROGYNOVA N 2MG/0.15Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesLorazepam
go.drugbank.com/drugs/DB00186ApprovedInvestigational[A957] It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in the USA in 1977. … The first historic FDA label approval is reported in 1985 by the company Mutual Pharm.[L5095]
Synonyms: o-Chloroxazepam, o-ChlorooxazepamProducts: Nu-loraz Tab 1mg, Nu-loraz Tab 2mgTioconazole
go.drugbank.com/drugs/DB01007ApprovedIn addition to being an antifungal, tioconazole also has antibacterial effects on certain Gram-positive cocci bacteria.[L50166] … Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane.
Mixtures: GYNOMAX L VAJINAL OVUL, 7 ADET, Gynecure Com.pk.vag Ont6.5%vulvar Crm1% W/wCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP3A InhibitorsCongenital Plasminogen Deficiency
go.drugbank.com/conditions/DBCOND0138725Drugs: PlasminogenSynonyms: Type I Plasminogen DeficiencyPyrithione
go.drugbank.com/drugs/DB06815ApprovedInvestigationalPyrithione zinc is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos. … It is not shown to have any significant estrogenic activity according to the _in vivo_ and _in vitro_ assays [A32163].
Mixtures: Z-plus Shampoo, Solep Premier Hi GroCategories: Heterocyclic Compounds, 1-RingOxygen
go.drugbank.com/drugs/DB09140ApprovedInvestigationalVet approvedOxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. … ability to take up and use gaseous oxygen.
Mixtures: Lung Diffusion Test Mix No Ne Co, Co-NE-O2-N2 MixtureProducts: N/A, Oxygen Compressed UN 1072 Refrigerated UN 1073Diabetes Mellitus, Insulin Dependent
go.drugbank.com/conditions/DBCOND0035532Drugs: Insulin porkSynonyms: Type I diabetes mellitus, Diabetes mellitus type I