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Deoxyribonuclease-2-alpha
go.drugbank.com/bio_entities/BE0011359TargetHumansNecessary for proper fetal development and for definitive erythropoiesis in fetal liver and bone marrow, where it degrades nuclear DNA expelled from erythroid precursor cells (PubMed:29259162)
Polypeptides: Deoxyribonuclease-2-alphaLysophosphatidylcholine acyltransferase 2
go.drugbank.com/bio_entities/BE0016122TargetEnzymeHumansAlso converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine (PC), a major component of cell membranes and a PAF precursor (By similarity). … Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position
Polypeptides: Lysophosphatidylcholine acyltransferase 2Synonyms: LPCAT-2, LPC acyltransferase 2Adenosine deaminase 2
go.drugbank.com/bio_entities/BE0020559EnzymeHumansAdenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surf...
Polypeptides: Adenosine deaminase 2Interleukin-2 receptor
go.drugbank.com/bio_entities/BE0027978TargetHumansReceptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. … Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity.
Polypeptides: Interleukin-2 receptor subunit alpha, Interleukin-2 receptor subunit betaSynonyms: IL-2-RA, IL-2 receptor subunit gammaCianidanol
go.drugbank.com/drugs/DB14086ApprovedInvestigationalWithdrawnAn antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
Synonyms: d-Catechin, D-CatecholCategories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-RingDermatophagoides pteronyssinus
go.drugbank.com/drugs/DB10401ApprovedInvestigationalThis combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Mixtures: SLITone ULTRA D. pteronyssinus/ D. farinae, Allergenic Extract Mixture Of Standardized Mites (5,000 Au/ml)Synonyms: AE-mite, dermatophagoides pteronyssinusATP-binding cassette sub-family B member 5
go.drugbank.com/bio_entities/BE0002369TargetTransporterHumansEnergy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells (PubMed:12960149, PubMed:15205344, PubMed:15899824, PubMed:22306008). Specifically present in limbal stem cells, where it plays ...
Polypeptides: ATP-binding cassette sub-family B member 5Potassium voltage-gated channel subfamily KQT member 5
go.drugbank.com/bio_entities/BE0002400TargetHumansPore-forming subunit of the voltage-gated potassium (Kv) channel broadly expressed in brain and involved in the regulation of neuronal excitability (PubMed:10787416, PubMed:10816588, PubMed:11159685, PubMed:28669405). Associates with KCN...
Polypeptides: Potassium voltage-gated channel subfamily KQT member 5Synonyms: KQT-like 5Rod cGMP 3',5'-cyclic phosphodiesterase subunit gamma
go.drugbank.com/bio_entities/BE0003556TargetHumansInhibitory gamma subunit of the rod-specific cGMP phosphodiesterase (PDE6) complex, which hydrolyzes 3',5'-cyclic GMP in the phototransduction cascade.
Polypeptides: Rod cGMP 3',5'-cyclic phosphodiesterase subunit gammaFunction: 3',5'-cyclic-nucleotide phosphodiesterase activityATP-binding cassette sub-family C member 5
go.drugbank.com/bio_entities/BE0003639TransporterTargetHumansATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Mediates ATP-dependent transport of endogenous metabolites such as cAMP and cGMP, folic acid a...
Polypeptides: ATP-binding cassette sub-family C member 5Synonyms: Multidrug resistance-associated protein 5