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Displaying results 5871 - 5880 of 10000 in total
  1. Target

    Beta-arrestin-2

    go.drugbank.com/bio_entities/BE0013128
    TargetHumans

    AP-2) in clathrin-coated pits (CCPs). … Increases ERK1/2 signaling in AGTR1- and AVPR2-mediated activation (reciprocal regulation). Involved in CCR7-mediated ERK1/2 signaling involving ligand CCL19.

    Polypeptides: Beta-arrestin-2Synonyms: Arrestin beta-2
  2. Target

    Urotensin-2 receptor

    go.drugbank.com/bio_entities/BE0020904
    TargetHumans

    G protein-coupled receptor for the vasoactive neuropeptides urotensin-2 and urotensin-2B (PubMed:14550283).

    Polypeptides: Urotensin-2 receptorSynonyms: UR-2-R
  3. Target

    Beta-secretase 2

    go.drugbank.com/bio_entities/BE0021401
    TargetHumans

    Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-assoc...

    Polypeptides: Beta-secretase 2Synonyms: Beta-site APP cleaving enzyme 2, Beta-site amyloid precursor protein cleaving enzyme 2
  4. Drug

    Ferric hydroxide

    go.drugbank.com/drugs/DB13423
    Investigational

    Products: FERIFER-40 ORAL COZELTI 40 MG/5 ML KAŞIK, 28 ADET, FERIFER 100 MG/5 ML ORAL COZELTI ICEREN KAŞIK, 20 ADET
  5. Drug

    Exametazime

    go.drugbank.com/drugs/DB11179
    Approved

    It acts as a chelating agent for the radioisotope technetium-99m to form a cationic complex. … Exametazime is a diagnostic radiopharmaceutical agent commonly used for the preparation of Tc99m Exametazime injection.

    Products: CERETEC FOR INJECTION 0.5 mg/vial, BRAIN - SPECT®
  6. Drug

    Glycine

    go.drugbank.com/drugs/DB00145
    ApprovedInvestigationalNutraceuticalVet approved

    A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.

    Mixtures: TRAVASOL PLUS 15% LIBRE DE BISULFITO, TRAVASOL PLUS 15% LIBRE DE BISULFITOProducts: GLICINA 1.5% SOLUCION DE IRRIGACION, GLICINA IRRIGACION 1.5% M/V
  7. Drug

    Testosterone undecanoate

    go.drugbank.com/drugs/DB13946
    ApprovedInvestigational

    Testosterone undecanoate is the ester prodrug of [testosterone] and has a mid-chain fatty acid at the carbon 17β position. … [L35970,L8932,L41355] Testosterone is a critical male hormone that is responsible for the normal growth and development of the male sex organs and for the maintenance of secondary sex characteristics

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: Nebido 1000 mg/4 ml Injektionslösung, Testomed 1000 mg/4 ml Injektionslösung
  8. Drug

    Topiramate

    go.drugbank.com/drugs/DB00273
    ApprovedInvestigational

    [L10550] Characteristics that distinguish topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and 40% of its mass accounted for by oxygen. … Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines.[A175249] It was initially approved by the FDA in 1996.

    Synonyms: 2,3:4,5-di-O-isopropylidene-β-D-fructopyranose sulfamate, 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamateCategories: P-glycoprotein substrates, Cytochrome P-450 CYP3A Inducers
  9. Pathway

    Acylcarnitine (5Z)-7-[(1S,5E)-5-[(2E)-oct-2-en-1-ylidene]-4-oxocyclopent-2-en-1-yl]hept-5-enoylcarnitine

    smpdb.ca/view/SMP0123550
    Metabolic

    (5Z)-7-[(1S,5E)-5-[(2E)-oct-2-en-1-ylidene]-4-oxocyclopent-2-en-1-yl]hept-5-enoylcarnitine is an acylcarnitine. … membrane to once again form (5Z)-7-[(1S,5E)-5-[(2E)-oct-2-en-1-ylidene]-4-oxocyclopent-2-en-1-yl]hept-5-enoyl-CoA and L-carnitine. (5Z)-7-[(1S,5E)-5-[(2E)-oct-2-en-1-ylidene]-4-oxocyclopent-2-en-1-yl]

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5, Carnitine O-palmitoyltransferase 2, mitochondrial
  10. Drug

    Etamsylate

    go.drugbank.com/drugs/DB13483
    Investigational

    Products: DICYNONE INJECTION 250 mg/2 ml, QUERCETOL® 250 MG/2 ML SOLUCION INYECTABLE.