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Displaying results 51 - 60 of 125 in total
  1. Target

    Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

    go.drugbank.com/bio_entities/BE0000445
    TargetHumans

    Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric

    Polypeptides: Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrialSynonyms: 3-methylcrotonyl-CoA carboxylase 1, 3-methylcrotonyl-CoA carboxylase biotin-containing subunit
  2. Target

    Propionyl-CoA carboxylase beta chain, mitochondrial

    go.drugbank.com/bio_entities/BE0000544
    TargetEnzymeHumans

    Propionyl-CoA carboxylase catalyzes the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl-CoA/(S)-methylmalonyl-CoA (PubMed:15890657, PubMed:6765947). … Propionyl-CoA carboxylase also significantly acts on butyryl-CoA/butanoyl-CoA, which is converted to ethylmalonyl-CoA/(2S)-ethylmalonyl-CoA at a much lower rate (PubMed:6765947).

    Polypeptides: Propionyl-CoA carboxylase beta chain, mitochondrialFunction: propionyl-CoA carboxylase activity
  3. Target

    Uncharacterized acyl-CoA thioester hydrolase HI_0827

    go.drugbank.com/bio_entities/BE0002679
    TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

    Polypeptides: Uncharacterized acyl-CoA thioester hydrolase HI_0827Function: long-chain fatty acyl-CoA hydrolase activity
  4. Target

    Peroxisomal trans-2-enoyl-CoA reductase

    go.drugbank.com/bio_entities/BE0002791
    TargetHumans

    Catalyzes the reduction of trans-2-enoyl-CoAs of varying chain lengths from 6:1 to 16:1, having maximum activity with 10:1 CoA. Has no 2,4-dienoyl-CoA reductase activity

    Polypeptides: Peroxisomal trans-2-enoyl-CoA reductaseSynonyms: 2,4-dienoyl-CoA reductase-related protein
  5. Target

    Propionyl-CoA carboxylase alpha chain, mitochondrial

    go.drugbank.com/bio_entities/BE0000492
    TargetHumans

    Propionyl-CoA carboxylase catalyzes the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl-CoA/(S)-methylmalonyl-CoA (PubMed:10101253, PubMed:6765947, PubMed:8434582). … Propionyl-CoA carboxylase also significantly acts on butyryl-CoA/butanoyl-CoA, which is converted to ethylmalonyl-CoA/(2S)-ethylmalonyl-CoA at a much lower rate (PubMed:6765947).

    Polypeptides: Propionyl-CoA carboxylase alpha chain, mitochondrial
  6. Target

    Enoyl-CoA delta isomerase 1, mitochondrial

    go.drugbank.com/bio_entities/BE0001764
    TargetHumans

    Together with the 2,4-dienoyl-CoA reductase (DECR) and the Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase (ECH1), they allow the reentrance of the enoyl-CoA into the beta-oxidation cycle (PubMed:26474213) … Able to isomerize both 3-cis (3Z) and 3-trans (3E) double bonds into the 2-trans (2E) form in a range of fatty enoyl-CoA species, with a preference for (3Z)-enoyl-CoAs over (3E)-enoyl-CoAs (PubMed:26474213

    Polypeptides: Enoyl-CoA delta isomerase 1, mitochondrialSynonyms: D3,D2-enoyl-CoA isomerase, Dodecenoyl-CoA isomerase
  7. Target

    1,4-Dihydroxy-2-naphthoyl-CoA synthase

    go.drugbank.com/bio_entities/BE0002684
    TargetMycobacterium tuberculosis

    Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).

    Polypeptides: 1,4-dihydroxy-2-naphthoyl-CoA synthaseSynonyms: DHNA-CoA synthase
  8. Target

    Propionyl-CoA carboxylase complex B subunit

    go.drugbank.com/bio_entities/BE0002846
    TargetStreptomyces coelicolor

    Polypeptides: Propionyl-CoA carboxylase complex B subunitFunction: acetyl-CoA carboxylase activity
  9. Target

    Acyl-CoA dehydrogenase, short-chain specific

    go.drugbank.com/bio_entities/BE0002938
    TargetMegasphaera elsdenii

    Has an optimum specificity for 4-carbon length fatty acyl-CoAs.

    Polypeptides: Acyl-CoA dehydrogenase, short-chain specificSynonyms: Butyryl-CoA dehydrogenase
  10. Target

    Short-chain specific acyl-CoA dehydrogenase, mitochondrial

    go.drugbank.com/bio_entities/BE0000762
    TargetHumans

    acetyl-CoA and allowing the production of energy from fats (By similarity). … Short-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into

    Polypeptides: Short-chain specific acyl-CoA dehydrogenase, mitochondrialSynonyms: Butyryl-CoA dehydrogenase