Search
Velpatasvir Action Pathway
smpdb.ca/view/SMP0125945Drug actionVelpatasvir is a NS5A inhibitor used to treat chronic hepatitis C infections in patients without cirrhosis or with compensated cirrhosis, used as part of combination therapy to treat chronic Hepatitis C. Notably, velpatasvir has a signif...
Boceprevir Action Pathway
smpdb.ca/view/SMP0125956Drug actionBoceprevir is a hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Hepatitis C virus lipoviroparticles enter target hepatocytes via receptor-mediated ...
Tolterodine Action Pathway
smpdb.ca/view/SMP0126381Drug actionTolterodine is a muscarinic receptor antagonist used to treat overactive bladder with urinary incontinence, urgency, and frequency. It can be found under the brand names Detrol and Detrusitol. Tolterodine is a competitive muscarinic rece...
Methylergometrine Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126513Drug actionMethylergometrine is a semisynthetic ergot alkaloid and a derivative of ergonovine. It is also known as methylergonovine. Methylergometrine acts directly on the smooth muscle of the uterus and increases the tone, rate, and amplitude of r...
Gq Muscarinic Smooth Muscle Contraction
smpdb.ca/view/SMP0126945PhysiologicalGq protein alpha subunit is a family of heterotrimeric G protein alpha subunits. This family is also commonly called the Gq/11 (Gq/G11) family or Gq/11/14/15 family to include closely related family members. G alpha subunits may be refer...
Gq Histaminic Smooth Muscle Contraction
smpdb.ca/view/SMP0126962PhysiologicalThe H1 receptor is a histamine receptor belonging to the family of rhodopsin-like G-protein-coupled receptors. This receptor is activated by the biogenic amine histamine. It is expressed in smooth muscles, on vascular endothelial cells, ...
Mirtazapine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0174888Drug actionMirtazapine is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines interf...
Dexbrompheniramine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0174889Drug actionDexbrompheniramine is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines...
Hydroxyzine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0174892Drug actionHydroxyzine is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines interf...
Brompheniramine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0174898Drug actionBrompheniramine is an H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, al...