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Transforming growth factor beta activator LRRC32
go.drugbank.com/bio_entities/BE0014554TargetHumansKey regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:19651619, PubMed:19750484, PubMed:22278742). As...
Synonyms: Leucine-rich repeat-containing protein 32Relaxin receptor 1
go.drugbank.com/bio_entities/BE0019700TargetHumansReceptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activ...
Synonyms: Leucine-rich repeat-containing G protein-coupled receptor 7Serine/threonine-protein kinase TNNI3K
go.drugbank.com/bio_entities/BE0009401TargetHumansMay play a role in cardiac physiology
Synonyms: Cardiac ankyrin repeat kinaseReceptor-interacting serine/threonine-protein kinase 4
go.drugbank.com/bio_entities/BE0009533TargetHumansSerine/threonine protein kinase (By similarity). Required for embryonic skin development and correct skin homeostasis in adults, via phosphorylation of PKP1 and subsequent promotion of keratinocyte differentiation and cell adhesion (By s...
Synonyms: Ankyrin repeat domain-containing protein 3Potassium chloride
go.drugbank.com/drugs/DB00761ApprovedInvestigationalWithdrawnA white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. The FDA withdrew its approval for the use of all solid oral dosage form dr...
Mixtures: Ringer-Lactat nach Hartmann B.Braun Infusionslösung, Ringer-Lactat nach Hartmann NORIDEM InfusionslösungCalcium chloride
go.drugbank.com/drugs/DB01164ApprovedInvestigationalCalcium chloride is an ionic compound of calcium and chlorine. It is highly soluble in water and it is deliquescent. It is a salt that is solid at room temperature, and it behaves as a typical ionic halide. It has several common applicat...
Mixtures: Ringer-Lactat nach Hartmann B.Braun Infusionslösung, Ringer-Lactat nach Hartmann NORIDEM InfusionslösungRelaxin receptor 2
go.drugbank.com/bio_entities/BE0017729TargetHumansReceptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3)
Synonyms: Leucine-rich repeat-containing G protein-coupled receptor 8E3 ubiquitin-protein ligase XIAP
go.drugbank.com/bio_entities/BE0001156TargetHumansMulti-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis...
Synonyms: Baculoviral IAP repeat-containing protein 4Amlodipine
go.drugbank.com/drugs/DB00381ApprovedInvestigationalAmlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyri...
Mixtures: TUSSORET TAG/NACHT KAPSELN, TUSSORET TAG/NACHT KAPSELNSodium chloride
go.drugbank.com/drugs/DB09153ApprovedInvestigationalVet approvedSodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the...
Mixtures: Ringer-Lactat nach Hartmann B.Braun Infusionslösung, Ringer-Lactat nach Hartmann NORIDEM Infusionslösung