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Displaying results 51 - 60 of 10000 in total
  1. Drug

    Minocycline

    go.drugbank.com/drugs/DB01017
    ApprovedInvestigational

    [A190681] It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria.

    Products: Ava-minocycline, AA-Minocycline 50mg Capsule
  2. Drug

    Benzoyl peroxide

    go.drugbank.com/drugs/DB09096
    ApprovedInvestigational

    [A18903,A233859] This treatment decreases keratin and sebum around follicles, as well as increasing turnover of epithelial cells. … Benzoyl peroxide is a commonly used drug in topical treatments for acne.

    Mixtures: Clindoxyl Adv Gel, 3 Step Acne System Well at WalgreensProducts: B P O COMBUSTIN GEL, PR Benzoyl Peroxide Wash
  3. Drug

    Chlorhexidine

    go.drugbank.com/drugs/DB00878
    ApprovedInvestigationalVet approvedWithdrawn

    Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. … [A190453] Topical chlorhexidine for disinfection, as well as oral rinses for dental use, carries activity against a broad range of pathogens including bacteria, yeasts, and viruses.

    Synonyms: 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide)Mixtures: CLORHEXIDINA AL 4% Y CETRIMIDA AL 1% JABÓN ANTISÉPTICO, Soluprep steril 2% w/v + 70% v/v Lösung zur Anwendung auf der Haut
  4. Drug

    Flecainide

    go.drugbank.com/drugs/DB01195
    ApprovedInvestigationalWithdrawn

    [A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. … [A186931] It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: Ag-flecainide, FLECAINIDACETAT AL 50MG
  5. Drug

    Zopiclone

    go.drugbank.com/drugs/DB01198
    ApprovedInvestigational

    Zopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesProducts: Ag-zopiclone, Ava-zopiclone
  6. Drug

    Timolol

    go.drugbank.com/drugs/DB00373
    ApprovedInvestigational

    [L6724] It is also used in tablet form as a drug to treat hypertension.[L6727] Timolol was first approved by the FDA in 1978. … Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes.

    Mixtures: DORZOLAMID AL COMP ATR, DORZOLAMID AL COMP ATRCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  7. Drug

    Alteplase

    go.drugbank.com/drugs/DB00009
    ApprovedInvestigational

    Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent.[L43125] It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. … [A252330,L43125] Alteplase is a purified glycoprotein of 527 amino acids expressed in Chinese hamster ovary (CHO) cells.

    Synonyms: t-PA, rt-PAMixtures: Activase RT-PA, Lysatec RT - Pa
  8. Drug

    Alprazolam

    go.drugbank.com/drugs/DB00404
    ApprovedIllicitInvestigational

    [A18125] Alprazolam has been mixed with alcohol as a drug of abuse to potentiate the sedative effects of the drug which may lead to coma and death. … Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.

    Mixtures: Sentrazolam AMCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  9. Drug

    Simvastatin

    go.drugbank.com/drugs/DB00641
    ApprovedInvestigational

    as well as the need for surgical revascularization or angioplasty following a heart attack. … Simvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of _Aspergillus terreus_.

    Mixtures: DUTEZEN SV 10 TABLETAS, DUTEZEN SV 40 TABLETASCategories: P-glycoprotein inhibitors, P-glycoprotein substrates
  10. Drug

    Dolutegravir

    go.drugbank.com/drugs/DB08930
    ApprovedInvestigational

    Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). … [L1035] On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named

    Mixtures: Triumeq PDCategories: P-glycoprotein substrates