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Displaying results 601 - 610 of 10000 in total
  1. Drug

    Phenytoin

    go.drugbank.com/drugs/DB00252
    ApprovedInvestigationalVet approved

    Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants. … [A189219,A35884] Both parenteral and oral formulations of phenytoin are available on the market.[A189219]

    Categories: Inducers of Drug Clearance, Metabolic Side Effects of Drugs and SubstancesProducts: Epilan-D 100 mg - Tabletten, Epilan-D 50 mg/ml - Ampullen
  2. Drug

    Eplerenone

    go.drugbank.com/drugs/DB00700
    ApprovedInvestigational

    The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of eplerenone. … Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative

    Products: EPLERENON AL 25MG FTA, EPLERENON AL 50MG FTA
  3. Drug

    Mesalazine

    go.drugbank.com/drugs/DB00244
    ApprovedInvestigational

    Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical agent … of mesalazine within microgranules [A174019].

    Products: MELAZ 500 MG TABLETA DE LIBERACION RETARDADA, PENTASA®1 G GRANULOS DE LIBERACION PROLONGADA
  4. Drug

    Tiotropium

    go.drugbank.com/drugs/DB01409
    ApprovedInvestigational

    Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma. … [A180163] Tiotropium was granted FDA approval on 30 January 2004.[L7084]

    Products: BROMURO DE TIOTROPIO 18 µG CÁPSULA, TIOSYNT BROMURO DE TIOTROPIO 18 MCG /POLVO PARA INHALACION
  5. Drug

    Norfloxacin

    go.drugbank.com/drugs/DB01059
    ApprovedInvestigational

    A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.

    Categories: Metabolic Side Effects of Drugs and SubstancesProducts: NORMED 400 - U, NORFLOXACIN AL 400MG
  6. Drug

    Ivabradine

    go.drugbank.com/drugs/DB09083
    ApprovedInvestigational

    Therefore, as ivabradine is designed as a "pure" heart rate-lowering drug by selectively acting on the If channels, it may offer a more favorable side effect profile due to its lower likelihood of causing … ≥70 beats per minute, who are not on beta-blockers due to contraindications or already receiving maximum beta-blocker dose.

    Products: IVABRADIN AL 5MG, IVABRADIN AL 7.5MG
  7. Drug

    Cefaclor

    go.drugbank.com/drugs/DB00833
    ApprovedInvestigational

    Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.

    Synonyms: 3-Chloro-7-D-(2-phenylglycinamido)-3-cephem-4-carboxylic acidProducts: Nu-cefaclor, Nu-cefaclor Capsules 250mg
  8. Drug

    Cyclobenzaprine

    go.drugbank.com/drugs/DB00924
    ApprovedInvestigational

    [A184982] It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from [Amitriptyline] by only a single double bond. … [A185039,A184982] Since its approval, it has remained relatively popular as an adjunctive, short-term treatment for acute skeletal muscle spasms secondary to musculoskeletal injury.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: (3-Dibenzo[a,d]cyclohepten-5-ylidene-propyl)-dimethyl-amine, N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-Δ5,γ-propylamine
  9. Drug

    Tamoxifen

    go.drugbank.com/drugs/DB00675
    ApprovedInvestigational

    [A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments. … Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.

    International brands: Nolvadex-DCategories: UGT2B7 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic Index
  10. Drug

    Dopamine

    go.drugbank.com/drugs/DB00988
    ApprovedInvestigational

    Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action. … One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine.

    Mixtures: INYECCION DE CLORHIDRATO DE DOPAMINA 800 MCG/ML DEXTROSA AL 5% UPS, INYECCION DE CLORHIDRATO DE DOPAMINA EN DEXTROSA AL 5% USP (1600 MCG/ML)Categories: Compounds used in a research, industrial, or household setting, Monoamine Oxidase A Substrates