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Brain Diseases
go.drugbank.com/conditions/DBCOND0028247Drugs: ValpromideSynonyms: Neurologic disorder NOS, Neurological disorder NOSCorticorelin ovine triflutate
go.drugbank.com/drugs/DB09067ApprovedHowever, if corticorelin injection does not result in an increase of plasma ACTH and cortisol, the patient is diagnosed with ectopic ACTH syndrome.
CSOM - Chronic Suppurative Otitis Media
go.drugbank.com/conditions/DBCOND0111419Synonyms: Otitis media chronic NOS, Chronic otitis media, NOSCyclopropane mycolic acid synthase 2
go.drugbank.com/bio_entities/BE0001211TargetMycobacterium tuberculosisIn the absence of MmaA2, CmaA2 has a non-specific cis-cyclopropanating activity and is able to catalyze the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic
Synonyms: SAM-MT5-fluorotryptophan
go.drugbank.com/drugs/DB03314Experimental5-fluorotryptophan can be used as substrate analogue to study enzyme mechanisms by NMR spectroscopy.
Sipagladenant
go.drugbank.com/drugs/DB17080InvestigationalKW-6356 is a selective antagonist of adenosine A2A receptors developed by Kyowa Kirin.[L43822]
ABBV-514
go.drugbank.com/drugs/DB17586InvestigationalABBV-514 is in development for the treatment of non-small cell lung cancer (NSCLC) and head and neck squamous cell carcinoma (HNSCC) as a single agent and in combination with a PD-1 inhibitor.[L45464]
SIG-001
go.drugbank.com/drugs/DB17826InvestigationalSIG-001 is a cultured human retinal pigment epithelial cell line (ARPE-19) genetically modified with a non-viral vector to express B domain deleted human factor VIII protein, encapsulated within two-layer
TST10088
go.drugbank.com/drugs/DB05151ExperimentalTST10088 has been designed and engineered by Twinstrand to contain a peptide switch that is specifically cleaved by the matrix metalloproteinases which are known to be involved in tumor growth and metastasis … These molecules efficiently kill cells by activating preprogrammed death pathways known as apoptosis.
Hematoma
go.drugbank.com/conditions/DBCOND0023542Drugs: Escin · Heparin · Horse chestnut · Levomenthol · Polysulfated glycosaminoglycan · Testosterone propionate +1 moreSynonyms: Hematoma NOS, Haematoma NOS