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Virus Specific T-Cell
go.drugbank.com/drugs/DB15735InvestigationalThese T-cells are then isolated from the donor and expanded in a culture to generate more VSTs. … Virus Specific T-Cells (VSTs) are a target therapy that are generated for specific viral antigens. These products are generated from virus-naive or virus-experienced autologous or allogenic sources.
CYP-001
go.drugbank.com/drugs/DB15739InvestigationalThese cells have advantage over other MSCs because a large amount can be obtained from a single healthy blood donor, negating the risks from donor-and expansion dependent variability. … CYP-001 is a mesenchymoangioblast (MCA)-derived mesenchymal stem cell (MSC) therapy that originates from the mesoderm.
Recombinant Bacterial ACE2 Receptors-like Enzyme
go.drugbank.com/drugs/DB15741InvestigationalB38-CAP is structured as a carboxypeptidase and derived from _Paenibacillus sp._ The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities to the mammalian ACE2
Stem-cell derived exosome vesicle products
go.drugbank.com/drugs/DB15743ExperimentalWhile many contain a conserved set of proteins, they also carry unique tissue type-specific proteins.
Synonyms: DB-001Recombinant human plasma gelsolin
go.drugbank.com/drugs/DB15746InvestigationalPlasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds left over from damaged tissues.
Oral Polio Vaccine
go.drugbank.com/drugs/DB15864InvestigationalThe oral polio vaccine (OPV) is a live attenuated vaccine containing a mixture of one or more strains of poliovirus serotypes. … After administration, OPV strains extensively multiply in the intestinal tract, becoming widely spread in the community to immunize a sizable proportion of those unvaccinated in the population[A220163]
Pentaglobin
go.drugbank.com/drugs/DB15865InvestigationalPentaglobin, also known as IgM-enriched immunoglobulin, falls under a group of polyclonal immunoglobulin preparations. … [A220173] It is comprised of [immunoglobulin G (IgG)](https://www.drugbank.ca/drugs/DB00028) and immunoglobulin A (IgA) while also being enriched by immunoglobulin M (IgM).[L16353]
CK0802
go.drugbank.com/drugs/DB15866InvestigationalCK0802 is an off-the-shelf product composed of allogeneic umbilical cord blood derived regulatory T-cells (T-Reg cells), which can be used intravenously and without HLA matching. On the surface of these T-Reg cells, T-cell lung homing ma...
Amniotic Epithelial Cells
go.drugbank.com/drugs/DB15868InvestigationalAmniotic epithelial cells (AEC) are multipotent stem-like cells derived from the basement collagenous membrane of the human amnion, the layer of the placenta closest to the fetus. These cells are potential candidates for allogeneic cell ...
Platelet Lysate
go.drugbank.com/drugs/DB15869InvestigationalBecause white cell antigens are low in prepared lysate, there is a minimized likelihood of immune responses.