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Tocilizumab
go.drugbank.com/drugs/DB06273ApprovedInvestigationalTocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. … [L12789] It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: ACTEMRA 400 MG/20 ML IV INFUZYONLUK COZELTI KONSANTRESI İÇEREN FLAKON, 1 ADET, ACTEMRA 400 MG/20 ML IV INFUZYONLUK COZELTI KONSANTRESI İÇEREN FLAKON, 4 ADETFerric derisomaltose
go.drugbank.com/drugs/DB15617ApprovedInvestigational[A190528] Ferric derisomaltose is a form of iron used in the treatment of iron deficiency. This drug is a complex of iron (III) hydroxide and derisomaltose. … Iron deficiency results when iron intake, iron stores, and loss of iron from the body do not adequately support production of erythrocytes, also known as red blood cells.
Products: MONOFER® SOLUTION FOR INJECTION OR INFUSION 100 MG/ML, Diafer 50 mg/ml InjektionslösungN-acylglucosamine 2-epimerase
go.drugbank.com/bio_entities/BE0000109TargetEnzymeHumansCatalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine (PubMed:10502668, PubMed:12499362, PubMed:9990133). Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyz...
Polypeptides: N-acylglucosamine 2-epimeraseSynonyms: GlcNAc 2-epimerase, N-acetyl-D-glucosamine 2-epimeraseApoptosis regulator Bcl-2
go.drugbank.com/bio_entities/BE0000246TargetHumansSuppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells (PubMed:1508712, PubMed:8183370). Regulates cell death by controlling the mitochondrial membrane permeability (PubMed:11368...
Polypeptides: Apoptosis regulator Bcl-2Retinol-binding protein 2
go.drugbank.com/bio_entities/BE0000505CarrierHumansIntracellular transport of retinol
Polypeptides: Retinol-binding protein 2Beta-2 adrenergic receptor
go.drugbank.com/bio_entities/BE0000694TargetHumansG protein-coupled receptor for catecholamines that couples to both G(s) and G(i) proteins, activating bifurcated signaling pathways (PubMed:2831218, PubMed:7915137). ADRB2 binds epinephrine (Epi) with an approximately 30-fold greater aff...
Polypeptides: Beta-2 adrenergic receptorSynonyms: Beta-2 adrenoceptor, Beta-2 adrenoreceptorAcetyl-CoA carboxylase 2
go.drugbank.com/bio_entities/BE0000702TargetHumansCatalyzes a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated
Polypeptides: Acetyl-CoA carboxylase 2DNA topoisomerase 2-alpha
go.drugbank.com/bio_entities/BE0000742TargetHumansKey decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken st...
Polypeptides: DNA topoisomerase 2-alphaAngiotensin-converting enzyme 2
go.drugbank.com/bio_entities/BE0000982TargetEnzymeHumansEssential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis (PubMed:27217402). Converts angiotensin...
Polypeptides: Angiotensin-converting enzyme 2Purine nucleoside phosphorylase 2
go.drugbank.com/bio_entities/BE0001556TargetEscherichia coli (strain K12)The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. This prot...
Polypeptides: Purine nucleoside phosphorylase 2