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Displaying results 621 - 630 of 1809 in total
  1. Drug

    Aluminum zirconium tetrachlorohydrex gly

    go.drugbank.com/drugs/DB11149
    ApprovedWithdrawn

    Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.

    Products: Old Spice Red Zone Clear Gel Antiperspirant
  2. Drug

    Aluminum sulfate

    go.drugbank.com/drugs/DB11239
    Approved

    Aluminum (Al), also spelled aluminum, chemical element, a lightweight, silvery-white metal of main Group 13 (IIIa, or boron group) of the periodic table . It is a chemical agent used in water purification, the pH regulation of garden soi...

  3. Drug

    Sucrose

    go.drugbank.com/drugs/DB02772
    ApprovedInvestigational

    A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons.

  4. Drug

    Nicorandil

    go.drugbank.com/drugs/DB09220
    ApprovedInvestigationalWithdrawn

    Nicorandil is a dual-action potassium channel opener that relaxes vascular smooth muscle through membrane hyperpolarization via increased transmembrane potassium conductance and increased intracellular

  5. Drug

    Alpha-1-proteinase inhibitor

    go.drugbank.com/drugs/DB00058
    ApprovedInvestigational

    Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.

  6. Drug

    Vitamin A

    go.drugbank.com/drugs/DB00162
    ApprovedInvestigationalNutraceuticalVet approved

    Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A i...

    Mixtures: Liqui Vita, Vita Plex Tab
  7. Drug

    Pectin

    go.drugbank.com/drugs/DB11158
    ApprovedInvestigationalVet approved

    Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants. It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4. The carboxylic group of the constituents of pectin...

    Products: Best Health Berry Soothers Throat Drops
  8. Drug

    Clobazam

    go.drugbank.com/drugs/DB00349
    ApprovedIllicitInvestigational

    [A256913] Unlike older 1,4-benzodiazepines, clobazam has a better side-effects profile, particularly less sedative and amnesic effects. … [A256868] Additionally, clobazam is believed to be a partial agonist to the GABA<sub>A</sub> receptor rather than non-selective full receptor agonists like 1,4-benzodiazepines, thus potentially explaining

    Categories: GABA-A Receptor Agonists
  9. Target

    Type-1 angiotensin II receptor

    go.drugbank.com/bio_entities/BE0000062
    TargetHumans

    Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney (PubMed:15611106, PubMed:1567413, PubMed:25913193, PubMed:26420482 … The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers

    Polypeptides: Type-1 angiotensin II receptorSynonyms: AT1 receptor, Angiotensin II type-1 receptor
  10. Target

    Peroxisome proliferator-activated receptor gamma

    go.drugbank.com/bio_entities/BE0000215
    TargetHumans

    Ligand-activated transcription factor that forms obligate heterodimers with the retinoic acid receptor and acts as a key regulator of biological processes, such as adipocyte differentiation, lipid metabolism … Ligand-binding results in a conformational change in the receptor, promoting dissociation of repressors and recruitment of coactivators, and subsequent activation of target gene expression (PubMed:16150867

    Polypeptides: Peroxisome proliferator-activated receptor gammaSynonyms: Nuclear receptor subfamily 1 group C member 3