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Cefaclor
go.drugbank.com/drugs/DB00833ApprovedInvestigationalSemisynthetic, broad-spectrum antibiotic derivative of cephalexin.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 3-Chloro-7-D-(2-phenylglycinamido)-3-cephem-4-carboxylic acidBrompheniramine
go.drugbank.com/drugs/DB00835ApprovedHistamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Mixtures: Bio T Pres-B, J-tan D PdCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingLoperamide
go.drugbank.com/drugs/DB00836ApprovedInvestigational[A251610] Loperamide has a chemical structure that is similar to diphenoxylate and haloperidol;[A6249] however, loperamide works on mu (μ)-opioid receptors to mediate its pharmacological actions. … [A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: A D, Imodium A-DFlurandrenolide
go.drugbank.com/drugs/DB00846ApprovedA corticosteroid used topically in the treatment of various skin disorders. It is usually employed as a cream or an ointment, and is also used as a polyethylene tape with an adhesive.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Drenison Tape M 170 4mcg Sq CmDacarbazine
go.drugbank.com/drugs/DB00851ApprovedInvestigationalAn antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma.
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic IndexSynonyms: 4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide, 4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamideBenzonatate
go.drugbank.com/drugs/DB00868Approved[A5790] Currently, benzonatate is the only non-narcotic antitussive available as a prescription drug. … [L11193] Although it not prone to drug misuse or abuse, benzonatate is associated with a risk for severe toxicity and overdose, especially in children.[A189513]
Categories: Decreased Tracheobronchial Stretch Receptor ActivitySynonyms: 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-butylaminobenzoate, p-butylaminobenzoic acid ω-O-methylnonaethyleneglycol esterDorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigationalDorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and
Mixtures: NEFRIDAXEM B+D, XOLATIM %2+ %0,5 GÖZ DAMLASI, ÇÖZELTİ ,5 ML,1 ŞİŞECategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingTerbutaline
go.drugbank.com/drugs/DB00871ApprovedInvestigational[A230328] It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients.[A230333,L32093,L32098] Terbutaline was granted FDA approval on 25 March 1974.[L32088]
Mixtures: BİCANA 1,5 MG/5 ML + 66,5 MG/5 ML ŞURUP, 100 ML, ULTRABRON T JARABECategories: Adrenergic beta-2 Receptor Agonists, Selective Beta 2-adrenergic AgonistsConivaptan
go.drugbank.com/drugs/DB00872ApprovedConivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). … Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2).
Categories: Antidiuretic Hormone Receptor Antagonists, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: 4'-((4,5-dihydro-2-methylimidazo(4,5-d)(1)benzazepin-6(1H)-yl)carbonyl)-2-biphenylcarboxanilideChlorothiazide
go.drugbank.com/drugs/DB00880ApprovedInvestigationalVet approvedA thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Categories: Heterocyclic Compounds, 2-RingSynonyms: 6-Chloro-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[1,2,4]thiadiazine-7-sulfonic acid amide, 6-chloro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide