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Adenylosuccinate synthetase isozyme 2
go.drugbank.com/bio_entities/BE0002228TargetHumansPlays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Polypeptides: Adenylosuccinate synthetase isozyme 2Synonyms: AdSS 2, AMPSase 2Mitochondrial glutamate carrier 2
go.drugbank.com/bio_entities/BE0002275TransporterHumansResponsible for the transport of glutamate from the cytosol into the mitochondrial matrix with the concomitant import of a proton (symport system)
Polypeptides: Mitochondrial glutamate carrier 2Synonyms: GC-2, Glutamate/H(+) symporter 2Putative pteridine reductase 2
go.drugbank.com/bio_entities/BE0002691TargetTrypanosoma cruziPolypeptides: Putative pteridine reductase 22-keto-3-deoxygluconokinase
go.drugbank.com/bio_entities/BE0003107TargetThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)Polypeptides: 2-keto-3-deoxygluconokinaseSynonyms: 2-keto-3-deoxy-gluconate kinase, 3-deoxy-2-oxo-D-gluconate kinaseLeukotriene B4 receptor 2
go.drugbank.com/bio_entities/BE0003489TargetHumansLow-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank ...
Polypeptides: Leukotriene B4 receptor 2Synonyms: LTB4-R 2Copper-transporting ATPase 2
go.drugbank.com/bio_entities/BE0003664TransporterHumansCopper ion transmembrane transporter involved in the export of copper out of the cells. It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload
Polypeptides: Copper-transporting ATPase 2Synonyms: Copper pump 2Penicillin-binding protein 2
go.drugbank.com/bio_entities/BE0003688TargetBacteroides fragilisPolypeptides: Penicillin-binding protein 2Adenylate cyclase type 2
go.drugbank.com/bio_entities/BE0003732TargetHumansCatalyzes the formation of the signaling molecule cAMP in response to G protein signaling (PubMed:15385642). Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in si...
Polypeptides: Adenylate cyclase type 2Synonyms: Adenylyl cyclase 2, ATP pyrophosphate-lyase 2Nuclear receptor coactivator 2
go.drugbank.com/bio_entities/BE0003740TargetHumansCoactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1) (PubMed:23508108, PubMed:8670870, PubMed:9430642).
Polypeptides: Nuclear receptor coactivator 2Synonyms: NCoA-2, Transcriptional intermediary factor 2Glycylpeptide N-tetradecanoyltransferase 2
go.drugbank.com/bio_entities/BE0003780TargetHumansAlso able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3' (PubMed:32103017).
Polypeptides: Glycylpeptide N-tetradecanoyltransferase 2Synonyms: NMT 2, Peptide N-myristoyltransferase 2