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Displaying results 631 - 640 of 10000 in total
  1. Pathway

    Acylcarnitine non-5-enoylcarnitine

    smpdb.ca/view/SMP0123416
    Metabolic

    non-5-enoylcarnitine is an acylcarnitine. … Once in the matrix, non-5-enoylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme found in the mitochondrial inner membrane to once again form non-5-enoyl-CoA and L-carnitine. non-5

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  2. Pathway

    Acylcarnitine non-3-enoylcarnitine

    smpdb.ca/view/SMP0123417
    Metabolic

    non-3-enoylcarnitine is an acylcarnitine. … Once in the matrix, non-3-enoylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme found in the mitochondrial inner membrane to once again form non-3-enoyl-CoA and L-carnitine. non-3

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  3. Pathway

    Acylcarnitine non-3-enedioylcarnitine

    smpdb.ca/view/SMP0123427
    Metabolic

    non-3-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, non-3-enedioyl-CoA reacts with L-carnitine to form non-3-enedioylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  4. Drug

    Chlorthalidone

    go.drugbank.com/drugs/DB00310
    ApprovedInvestigational

    Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of the Na+/Cl− symporter in the distal convoluted tubule cells in the kidney. … [A173884, A173887] Further studies have indicated that low-dose thiazides are as good as, and in some secondary endpoints, better than β-blockers, ACE inhibitors, Calcium Channel Blockers or ARBs.

    Categories: Non Potassium Sparing Diuretics, Low-Ceiling Diuretics, Excl. Thiazides
  5. Drug

    Carbon monoxide

    go.drugbank.com/drugs/DB11588
    ApprovedInvestigational

    This use of CO has been generally recognized as safe (GRAS) in several packaging applications for fresh meat products. … In New Zealand, the use of carbon monoxide in fish preparation has been banned, as it may mask the effects of food spoilage and bacterial growth [L2539].

    Mixtures: Lung Diffusion Test Mix No Ne Co, Co-NE-O2-N2 Mixture
  6. Drug

    Ezetimibe

    go.drugbank.com/drugs/DB00973
    ApprovedInvestigational

    [A15202] By interfering with the intestinal uptake of cholesterol and phytosterols, ezetimibe reduces the delivery of intestinal cholesterol to the liver.[L11347] … cholesterol-reducing compounds including statins and bile acid sequestrants, ezetimibe has a distinct mechanism of action involving the sterol transporter Niemann-Pick C1-Like 1 (NPC1L1), and is unique in that it does not

    Mixtures: BLODIVIT-EZ, VASOTENAL EZCategories: Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia
  7. Drug

    Hydantocidin-5'-phosphate

    go.drugbank.com/drugs/DB02493
    Experimental

    Synonyms: [(5S,7R,8S,9R)-8,9-dihydroxy-2,4-dioxo-6-oxa-1,3-diazaspiro[4.4]non-7-yl]methyl dihydrogen phosphate
  8. Drug

    Diclofenac

    go.drugbank.com/drugs/DB00586
    ApprovedInvestigationalVet approved

    Diclofenac was first approved by the FDA in July 1988 under the trade name Voltaren, marketed by Novartis (previously Ciba-Geigy).[L7360] … Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).

    International brands: Nu-DicloCategories: Anti-Inflammatory Agents, Non-Steroidal (Non-Selective), Analgesics, Non-Narcotic
  9. Target

    DAN domain family member 5

    go.drugbank.com/bio_entities/BE0005538
    TargetHumans

    Antagonist of the extracellular signaling protein NODAL, which is required for correct left-right patterning during embryonic development (By similarity). Antagonist of BMP and TGF-beta signaling (PubMed:33587337). Independently of its r...

    Polypeptides: DAN domain family member 5
  10. Drug

    Luliconazole

    go.drugbank.com/drugs/DB08933
    ApprovedInvestigational

    Luliconazole is a topical antifungal agent that acts by unknown mechanisms but is postulated to involve altering the synthesis of fungi cell membranes. … It was approved by the FDA (USA) in November 2013 and is marketed under the brand name Luzu. Luliconazole is also approved in Japan.