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Displaying results 641 - 650 of 1803 in total
  1. Target

    Cytochrome c oxidase copper chaperone

    go.drugbank.com/bio_entities/BE0008686
    CarrierHumans

    Copper metallochaperone involved in the assembly of cytochrome c oxidase (respiratory chain complex IV, CIV) (PubMed:15229189, PubMed:19393246, PubMed:31903891, PubMed:35750769). … Binds two copper ions and delivers them to metallochaperones SCO1 and SCO2, which co-chaperone the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2), and to metallochaperone

    Polypeptides: Cytochrome c oxidase copper chaperoneFunction: copper chaperone activity
  2. Drug

    Pyridoxine

    go.drugbank.com/drugs/DB00165
    ApprovedInvestigationalNutraceuticalVet approved

    Although all six of these compounds should technically be referred to as vitamin B6, the term vitamin B6 is commonly used interchangeably with just one of them, pyridoxine [A32836].

    Mixtures: Cavan One, Folet OneCategories: Vitamin B Complex
  3. Drug

    Minnelide

    go.drugbank.com/drugs/DB17309
    Investigational

    Synonyms: Trisoxireno(4b,5:6,7:8a,9)phenanthro(1,2-c)furan-1(3h)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-8b-methyl-6a-(1-methylethyl)-6-((phosphonooxy)methoxy)-, sodium salt (1:2), (3bs,4as,5ar,6r,6as,7as,7bs,
  4. Drug

    Acetylsalicylic acid

    go.drugbank.com/drugs/DB00945
    ApprovedInvestigationalVet approved

    Also known as Aspirin, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platele...

    Mixtures: Care One migraine relief, Care One headache relief added strengthProducts: Care One Aspirin
  5. Indication

    Nosocomial Pneumonia caused by Acinetobacter Baumannii-calcoaceticus Complex

    go.drugbank.com/conditions/DBCOND0159090
    Drugs: Durlobactam · Sulbactam
    Synonyms: Nosocomial Pneumonia caused by Acinetobacter Baumannii-calcoaceticus Complex
  6. Target

    Amine oxidase [copper-containing] 3

    go.drugbank.com/bio_entities/BE0001002
    TargetEnzymeHumans

    Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia (PubMed:19588076, PubMed:24304424, PubMed:9653080). Has a preference for the primary mo...

    Polypeptides: Amine oxidase [copper-containing] 3Synonyms: Copper amine oxidase, Amine oxidase copper-containing 3
  7. Target

    Polycomb complex protein BMI-1

    go.drugbank.com/bio_entities/BE0013109
    TargetHumans

    Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development … In the PRC1-like complex, regulates the E3 ubiquitin-protein ligase activity of RNF2/RING2 (PubMed:15386022, PubMed:21772249, PubMed:26151332)

    Polypeptides: Polycomb complex protein BMI-1
  8. Drug

    Insulin icodec

    go.drugbank.com/drugs/DB16693
    ApprovedInvestigational

    [A264093] These modifications - which cause increased serum albumin binding and attenuated insulin receptor affinity - result in a mean half-life of approximately 196 hours, allowing for once-weekly administration

  9. Drug

    Cinolazepam

    go.drugbank.com/drugs/DB01594
    Investigational

    Cinolazepam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant activity. It is not approved in Canada or America.

    Synonyms: 1-(2-cyanoethyl)-7-chloro-3-hydroxy-5-(2'-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
  10. Target

    Chain A, Red Copper Protein Nitrosocyanin

    go.drugbank.com/bio_entities/BE0002711
    TargetNitrosomonas europaea (strain ATCC 19718 / NBRC 14298)

    Polypeptides: Chain A, Red Copper Protein Nitrosocyanin