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Displaying results 651 - 660 of 7283 in total
  1. Target

    Cytochrome c oxidase copper chaperone

    go.drugbank.com/bio_entities/BE0008686
    CarrierHumans

    Copper metallochaperone involved in the assembly of cytochrome c oxidase (respiratory chain complex IV, CIV) (PubMed:15229189, PubMed:19393246, PubMed:31903891, PubMed:35750769). … Binds two copper ions and delivers them to metallochaperones SCO1 and SCO2, which co-chaperone the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2), and to metallochaperone

    Polypeptides: Cytochrome c oxidase copper chaperoneFunction: copper chaperone activity
  2. Drug

    Minoxidil

    go.drugbank.com/drugs/DB00350
    ApprovedInvestigational

    A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.

    Mixtures: FOLISTER COMPLEX HAIR LOTION (R), FOLISTER COMPLEX HAIR LOTION (R)Products: Vitadil-5A, Vitadil-2A
  3. Drug

    Riboflavin

    go.drugbank.com/drugs/DB00140
    ApprovedInvestigationalNutraceuticalVet approved

    Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms ...

    Mixtures: One A Day Tab, Extra Once A DayCategories: Vitamin B Complex
  4. Drug

    Triclosan

    go.drugbank.com/drugs/DB08604
    Approved

    An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. … It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards

    Products: Dg Body Antibacterial, Dt Antibacterial Hand
  5. Drug

    Migalastat

    go.drugbank.com/drugs/DB05018
    ApprovedInvestigational

    Fabry disease is a rare, progressive genetic disorder characterized by a defective GLA gene that causes a deficiency in the enzyme alpha-Galactosidase A (alpha-Gal A). … [L47036,L47057] As of August 2018, migalastat under Amicus Therapeutics' brand name Galafold is currently approved in Australia, Canada, European Union, Israel, Japan, South Korea, Switzerland, and

    Categories: Alpha-Galactosidase A (alpha-Gal A) Pharmacological Chaperones
  6. Drug

    Selenium

    go.drugbank.com/drugs/DB11135
    ApprovedInvestigationalVet approved

    species [FDA Label] … Selenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen

    Mixtures: Extra Once A Day, Maximum Once A DayCategories: Compounds used in a research, industrial, or household setting
  7. Indication

    Nosocomial Pneumonia caused by Acinetobacter Baumannii-calcoaceticus Complex

    go.drugbank.com/conditions/DBCOND0159090
    Drugs: Durlobactam · Sulbactam
    Synonyms: Nosocomial Pneumonia caused by Acinetobacter Baumannii-calcoaceticus Complex
  8. Drug

    Calcium Phosphate

    go.drugbank.com/drugs/DB11348
    ApprovedInvestigational

    Calcium phosphate is typically available as an over the counter supplement, antacid, or as an added ingredient in some toothpastes [FDA Label] [L851].

    Mixtures: Folcal DHA, Folcal DHACategories: Compounds used in a research, industrial, or household setting
  9. Drug

    Pyridoxine

    go.drugbank.com/drugs/DB00165
    ApprovedInvestigationalNutraceuticalVet approved

    As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. … Vitamin B6, principally in its biologically active coenzyme form pyridoxal 5'-phosphate, is involved in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the

    Mixtures: Niaacinamide Azelaic AC TURMER FA B6 Zinc Ox Copper, One A Day TabCategories: Vitamin B Complex
  10. Drug

    Carbidopa

    go.drugbank.com/drugs/DB00190
    ApprovedInvestigational

    Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. … [T394] The first approved product by the FDA containing only carbidopa was developed by Amerigens Pharmaceuticals Ltd and approved on 2014.

    Mixtures: Aa-levocarb CR, Aa-levocarb CR