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Mitiglinide
go.drugbank.com/drugs/DB01252InvestigationalMitiglinide is a drug for the treatment of type 2 diabetes. It may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels.
Categories: Heterocyclic Compounds, 2-RingArformoterol
go.drugbank.com/drugs/DB01274ApprovedArformoterol is a bronchodilator. It works by relaxing muscles in the airways to improve breathing.
Mixtures: AIRBIR 3/100 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL, 120 KPS, AIRBIR 3/100 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL, 60 KPSCategories: Cytochrome P-450 Substrates, Adrenergic beta-2 Receptor AgonistsPramlintide
go.drugbank.com/drugs/DB01278ApprovedInvestigationalPramlintide is a relatively new adjunct treatment for diabetes (both type 1 and 2), developed by Amylin Pharmaceuticals. … It is derived from amylin, a hormone that is released into the bloodstream, in a similar pattern as insulin, after a meal. Like insulin, amylin is deficient in individuals with diabetes.
Glisoxepide
go.drugbank.com/drugs/DB01289InvestigationalGlisoxepide is one of the sulphonamide-derived oral antidiabetic drugs. It inhibits the uptake of bile acids into isolated rat hepatocytes. However it inhibits taurocholate uptake only in the absence of sodium ions. Glisoxepide uptake co...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesPractolol
go.drugbank.com/drugs/DB01297ApprovedA beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias.
Categories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor AntagonistsSynonyms: 1-(4-acetamidophenoxy)-3-isopropylamino-2-propanol, N-(4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)acetamideSulfacytine
go.drugbank.com/drugs/DB01298ApprovedSulfacytine is a short-acting sulfonamide. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. … Sulfacytine is a competitive inhibitor of the enzyme dihydropteroate synthetase.
Synonyms: 1-ethyl-N-sulfanilylcytosine, 1-ethyl N4-sulfanilylcytosinForasartan
go.drugbank.com/drugs/DB01342ExperimentalAs angiotensin II is a vasoconstrictor which also stimulates the synthesis and release of aldosterone, blockage of its effects results in a decreases in systemic vascular resistance. … Forasartan, a specific angiotensin II antagonist, is used alone or with other antihypertensive agents to treat hypertension.
Categories: Heterocyclic Compounds, 1-Ring, Angiotensin II Type 1 Receptor BlockersTasosartan
go.drugbank.com/drugs/DB01349ExperimentalTasosartan is a long-acting angiotensin II (AngII) receptor blocker. Its long duration of action has been attributed to its active metabolite enoltasosartan.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingAprobarbital
go.drugbank.com/drugs/DB01352ExperimentalIllicitA primary treatment indicated for the use of aprobarbital was subsequently insomnia. … Aprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant effects.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersSynonyms: 5-(1-methylethyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione, 5-allyl-5-isopropylbarbituric acidButobarbital
go.drugbank.com/drugs/DB01353ApprovedIllicitButobarbital is a sedative and a hypnotic drug.
Categories: Heterocyclic Compounds, 1-Ring