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Theophylline
go.drugbank.com/drugs/DB00277ApprovedInvestigationalA methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine recep...
Products: Quibron-T, Quibron T/SRLevonordefrin
go.drugbank.com/drugs/DB06707ApprovedInvestigationalLevonordefrin acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry.
Oxiconazole
go.drugbank.com/drugs/DB00239ApprovedOxiconazole is an antifungal agent that is commonly found in topical formulations. It is marketed under the brand names Oxistat and Oxistat, and is used in the treatment of various skin infections such as athlete's foot, jock itch and ri...
Synonyms: 2',4'-Dichloro-2-imidazol-1-ylacetophenone (Z)-[O-(2,4-dichlorobenzyl)oxime]Indium In-111 chloride
go.drugbank.com/drugs/DB09490ApprovedIt is supplied as a sterile, pyrogen-free solution of Indium ("'In) Chloride in O.04M HCI.
Amodiaquine
go.drugbank.com/drugs/DB00613ApprovedInvestigationalA 4-aminoquinoquinoline compound with anti-inflammatory properties.
Petrelintide
go.drugbank.com/drugs/DB19442InvestigationalPetrelintide is under investigation in clinical trial NCT06662539 (Once-weekly Petrelintide Versus Placebo for Obesity or Overweight With Co-morbidities).
Pentosan polysulfate
go.drugbank.com/drugs/DB00686ApprovedInvestigationalPentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.
Synonyms: 4-O-METHYL-.ALPHA.-D-GLUCURONO-.BETA.-D-XYLAN, HYDROGEN SULFATE, 4-O-METHYL-.ALPHA.-D-GLUCURONO-.BETA.-D-XYLAN, HYDROGEN SULPHATEGC-373
go.drugbank.com/drugs/DB15797ExperimentalGC-373 has been shown to inhibit the M<sup>pro</sup> target in various coronavirus strains, including feline, mink, and ferret M<sup>pro</sup> [A219041].
Bardoxolone
go.drugbank.com/drugs/DB12651InvestigationalBardoxolone has been used in trials studying the treatment of LYMPHOMA and Solid Tumors. It is a synthetic triterpenoid and a highly potent activator of redox-sensitive signaling pathways that induce programmed cell death (apoptosis) in ...
AX200
go.drugbank.com/drugs/DB05093InvestigationalAX200, which has been developed for the treatment of stroke, is the most advanced drug candidate and is halfway through the process of gaining clinical approval. The expression of the endogenous AX200 protein in the brain is increased af...