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Cysteinyl leukotriene receptor 2
go.drugbank.com/bio_entities/BE0000099TargetHumansReceptor for cysteinyl leukotrienes. The response is mediated via a G protein that activates a phosphatidylinositol-calcium second messenger system.
Polypeptides: Cysteinyl leukotriene receptor 2Synonyms: G protein-coupled receptor HG57, G protein-coupled receptor GPCR21Lutropin-choriogonadotropic hormone receptor
go.drugbank.com/bio_entities/BE0000134TargetHumansReceptor for lutropin-choriogonadotropic hormone (PubMed:11847099). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11847099)
Polypeptides: Lutropin-choriogonadotropic hormone receptorSynonyms: Luteinizing hormone receptorRetinoic acid receptor gamma
go.drugbank.com/bio_entities/BE0000144TargetHumansReceptor for retinoic acid.
Polypeptides: Retinoic acid receptor gammaSynonyms: Nuclear receptor subfamily 1 group B member 3Toll-like receptor 7
go.drugbank.com/bio_entities/BE0000155TargetHumansEndosomal receptor that plays a key role in innate and adaptive immunity (PubMed:14976261, PubMed:32433612).
Polypeptides: Toll-like receptor 7Gonadotropin-releasing hormone receptor
go.drugbank.com/bio_entities/BE0000203TargetHumansThis receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling … Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH
Polypeptides: Gonadotropin-releasing hormone receptorSynonyms: GnRH receptorActivin receptor type-1
go.drugbank.com/bio_entities/BE0000264TargetHumansAs a type I receptor, forms heterotetrameric receptor complexes with the type II receptors AMHR2, ACVR2A or ACVR2B (PubMed:17911401). … Bone morphogenetic protein (BMP) type I receptor that is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation
Polypeptides: Activin receptor type-1Synonyms: Activin receptor type I, Activin receptor-like kinase 2Alpha-2A adrenergic receptor
go.drugbank.com/bio_entities/BE0000289TargetHumansAlpha-2 adrenergic receptors are G protein-coupled receptors for catecholamines that activate the G(i/o) protein pathway, thereby promoting adenylyl cyclase inhibition, ERK1/2 stimulation, and voltage-gated calcium channels suppression (...
Polypeptides: Alpha-2A adrenergic receptorSynonyms: Alpha-2 adrenergic receptor subtype C10Melatonin receptor type 1B
go.drugbank.com/bio_entities/BE0000327TargetHumansHigh affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. … The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity
Polypeptides: Melatonin receptor type 1BSynonyms: Mel1b receptorALK tyrosine kinase receptor
go.drugbank.com/bio_entities/BE0000359TargetHumansNeuronal receptor tyrosine kinase that is essentially and transiently expressed in specific regions of the central and peripheral nervous systems and plays an important role in the genesis and differentiation … MDK-binding induces phosphorylation of the ALK target insulin receptor substrate (IRS1), activates mitogen-activated protein kinases (MAPKs) and PI3-kinase, resulting also in cell proliferation induction
Polypeptides: ALK tyrosine kinase receptorCholecystokinin receptor type A
go.drugbank.com/bio_entities/BE0000402TargetHumansReceptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. … This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system
Polypeptides: Cholecystokinin receptor type ASynonyms: CCK-A receptor, Cholecystokinin-1 receptor