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Displaying results 6741 - 6750 of 9325 in total
  1. Drug

    MD-0727

    go.drugbank.com/drugs/DB05948
    Investigational

    MD-0727 is a novel, potent cholesterol absorption inhibitor (CAI) under investigation for the treatment of hypercholesterolemia (high cholesterol.

  2. Drug

    Cilobradine

    go.drugbank.com/drugs/DB20039
    Investigational

    The usage of the INN stem '-bradine' in the name indicates that Cilobradine is a bradycardic agent. … Cilobradine is under investigation in clinical trial NCT02264041 (Effect of Cytochrome P 450 3A4 Inhibition by Itraconazole on the Single Oral Dose Pharmacokinetics of Cilobradine).

  3. Drug

    Tunodafil

    go.drugbank.com/drugs/DB21576
    Investigational

    The usage of the INN stem '-afil' in the name indicates that Tunodafil is a inhibitor of phosphodiesterase PDE5 with vasodilator action. … Tunodafil is under investigation in clinical trial NCT05976503 (A Study of the Interaction of Tunodafil Hydrochloride Tablets and Alcohol). Tunodafil has a monoisotopic molecular weight of 487.23 Da.

  4. Drug

    FRAX597

    go.drugbank.com/drugs/DB31734
    Experimental

    FRAX597 is a small molecule drug that inhibits the p21-activated kinases (PAKs).[A274673, A274678]

  5. Drug

    D-JNKI-1

    go.drugbank.com/drugs/DB05660
    Investigational

    A synthetic, cell permeable peptide that blocks the MAPK-JNK signal pathway; has potential therapeutic value for long-term protection of both the morphological integrity and physiological function of the

  6. Drug

    Ancriviroc

    go.drugbank.com/drugs/DB19773
    Experimental

    The usage of the INN stem '-viroc' in the name indicates that Ancriviroc is a CCR5 (Chemokine CC motif receptor 5) receptor antagonist. Ancriviroc has a monoisotopic molecular weight of 556.2 Da.

  7. Drug

    Diclofenac etalhyaluronate

    go.drugbank.com/drugs/DB20937
    Experimental

    The usage of the INN stem '-ac' in the name indicates that Diclofenac etalhyaluronate is a anti-inflammatory agent, ibufenac derivative.

  8. Drug

    Xemilofiban

    go.drugbank.com/drugs/DB21058
    Experimental

    The usage of the INN stem '-fiban' in the name indicates that Xemilofiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).

  9. Drug

    Imdatifan

    go.drugbank.com/drugs/DB21643
    Experimental

    The usage of the INN stem '-tifan' in the name indicates that Imdatifan is a hypoxia inducible factor (HIF)-2alpha (HIF-2a) inhibitor. Imdatifan has a monoisotopic molecular weight of 385.05 Da.

  10. Drug

    Eritoran

    go.drugbank.com/drugs/DB04933
    Investigational

    Eritoran is a structural analogue of the lipid A portion of lipopolysaccharide (LPS). It is being developed by Eisai Research Institute of Boston for the treatment of severe sepsis.