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Displaying results 6771 - 6780 of 10000 in total
  1. Target

    Nectin-4

    go.drugbank.com/bio_entities/BE0009798
    TargetHumans

    Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells

    Polypeptides: Nectin-4Synonyms: Nectin cell adhesion molecule 4, Poliovirus receptor-related protein 4
  2. Target

    Phosphodiesterase 4

    go.drugbank.com/bio_entities/BE0011004
    TargetHumans

    Hydrolyzes the second messenger 3',5'-cyclic AMP (cAMP), which is a key regulator of many important physiological processes

    Polypeptides: 3',5'-cyclic-AMP phosphodiesterase 4A, 3',5'-cyclic-AMP phosphodiesterase 4BFunction: 3',5'-cyclic-AMP phosphodiesterase activity, 3',5'-cyclic-AMP phosphodiesterase activity
  3. Drug

    Vitamin A

    go.drugbank.com/drugs/DB00162
    ApprovedInvestigationalNutraceuticalVet approved

    Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.

    Synonyms: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol, Vitamin A AlcoholInternational brands: Chocola A
  4. Drug

    Brotizolam

    go.drugbank.com/drugs/DB09017
    ApprovedWithdrawn

    Brotizolam is indicated for 2-4 weeks of treatment for severe or debilitating insomnia. … Brotizolam is a sedative-hypnotic thienodiazepine drug which is a benzodiazepine analog. It demonstrates anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant effects.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingInternational brands: Brotizolam M
  5. Target

    Hexokinase-4

    go.drugbank.com/bio_entities/BE0001056
    TargetEnzymeHumans

    Catalyzes the phosphorylation of hexose, such as D-glucose, D-fructose and D-mannose, to hexose 6-phosphate (D-glucose 6-phosphate, D-fructose 6-phosphate and D-mannose 6-phosphate, respectively) (PubMed:11916951, PubMed:15277402, PubMed...

    Polypeptides: Hexokinase-4
  6. Target

    Stathmin-4

    go.drugbank.com/bio_entities/BE0004003
    TargetHumans

    Exhibits microtubule-destabilizing activity

    Polypeptides: Stathmin-4
  7. Target

    Reticulon-4

    go.drugbank.com/bio_entities/BE0010844
    TargetHumans

    Required to induce the formation and stabilization of endoplasmic reticulum (ER) tubules (PubMed:24262037, PubMed:25612671, PubMed:27619977). They regulate membrane morphogenesis in the ER by promoting tubular ER production (PubMed:24262...

    Polypeptides: Reticulon-4
  8. Target

    Mucin-4

    go.drugbank.com/bio_entities/BE0018599
    TargetHumans

    Membrane-bound mucin, a family of highly glycosylated proteins that constitute the major component of the mucus, the slimy and viscous secretion covering epithelial surfaces (PubMed:10880978). These glycoproteins play important roles in ...

    Polypeptides: Mucin-4Synonyms: MUC-4
  9. Drug

    Hydrocortisone succinate

    go.drugbank.com/drugs/DB14545
    ApprovedInvestigational

    Synonyms: Cortisol 21-(hydrogen succinate)Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inducers
  10. Drug

    Enfortumab vedotin

    go.drugbank.com/drugs/DB13007
    ApprovedInvestigational

    [L10836] It is comprised of a fully human monoclonal antibody targeted against Nectin-4 and a microtubule-disrupting chemotherapeutic agent, monomethyl auristatin E (MMAE), joined by a protease-cleavable … [L10836] It is similar to [brentuximab vedotin], another antibody conjugated with MMAE that targets CD-30 instead of Nectin-4.

    Categories: Nectin-4-directed Antibodies, P-glycoprotein substratesProducts: PADCEV 20 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ , 1 ADET, PADCEV 30 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ , 1 ADET