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Displaying results 6801 - 6810 of 10000 in total
  1. Drug

    AVR-RD-05

    go.drugbank.com/drugs/DB18631
    Experimental

    It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII). … AVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced _ex vivo_ with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme.

  2. Drug

    Lactobacillus plantarum

    go.drugbank.com/drugs/DB11360
    Investigational

    *Lactobacillus plantarum* is a member of Lactobacillus, or lactic acid bacteria, that it is widely used in the food industry as a microbial starter and probiotic microorganism. … It is considered to be one of versatile species that carry out fermentative and metabolic processes, while exhibiting an antagonistic activity against pathogenic and spoilage microorganisms.

  3. Drug

    Cirazoline

    go.drugbank.com/drugs/DB09202
    Experimental

    It is an agonist of α1A, partial agonist of α1B and α1D, and a nonselective antagonist of α2. … It is believed that this combination of properties could make cirazoline an effective vasoconstricting agent.

  4. Drug

    Flovagatran

    go.drugbank.com/drugs/DB05714
    Experimental

  5. Drug

    Thrombopoietin

    go.drugbank.com/drugs/DB06534
    Investigational

  6. Drug

    Estradiol sulfamate

    go.drugbank.com/drugs/DB06597
    Investigational

  7. Drug

    Ilepatril

    go.drugbank.com/drugs/DB06604
    Investigational

  8. Drug

    Clazosentan

    go.drugbank.com/drugs/DB06677
    Investigational

  9. Drug

    Olenasufligene relduparvovec

    go.drugbank.com/drugs/DB16264
    Investigational

    Olenasufligene relduparvovec is under investigation in clinical trial NCT03612869 (Study of aavrh10-h.sgsh Gene Therapy in Patients With Mucopolysaccharidosis Type IIIA (MPS IIIA)). … It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene.[L46671]

  10. Drug

    Candoxatril

    go.drugbank.com/drugs/DB00616
    Experimental

    Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.

    Synonyms: [4(S)-cis]-4-[[[1-[3-[(2,3-dihydro-1H-Indeb5-yl)oxy]-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentyl]carbonyl]amino]cyclohexanecarboxylic acid