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Displaying results 6901 - 6910 of 10000 in total
  1. Drug

    Gilteritinib

    go.drugbank.com/drugs/DB12141
    ApprovedInvestigational

    [A40036] It is a pyrazinecarboxamide derivative that showed high selectivity to FLT3 preventing the c-Kit -driven myelosuppression observed in other therapies. … Gilteritinib, also known as ASP2215, is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and potency when compared with other agents from this group.

    Categories: fms-Like Tyrosine Kinase 3, antagonists & inhibitors, MATE 1 InhibitorsProducts: XOSPATA 40 MG FİLM KAPLI TABLET, 84 ADET, XOSPATA® FILM-COATED TABLETS 40MG
  2. Target

    Monocarboxylate transporter 4

    go.drugbank.com/bio_entities/BE0000449
    TargetTransporterHumans

    Proton-dependent transporter of monocarboxylates such as L-lactate and pyruvate (PubMed:11101640, PubMed:23935841, PubMed:31719150). Plays a predominant role in L-lactate efflux from highly glycolytic cells (By similarity)

    Polypeptides: Monocarboxylate transporter 4Synonyms: MCT 4, Solute carrier family 16 member 3
  3. Target

    Carbonic anhydrase 4

    go.drugbank.com/bio_entities/BE0000535
    TargetEnzymeHumans

    Catalyzes the reversible hydration of carbon dioxide into bicarbonate and protons and thus is essential to maintaining intracellular and extracellular pH (PubMed:15563508, PubMed:16686544, PubMed:16807956, PubMed:17127057, PubMed:1731404...

    Polypeptides: Carbonic anhydrase 4
  4. Target

    Phenylalanine-4-hydroxylase

    go.drugbank.com/bio_entities/BE0000753
    TargetEnzymeHumans

    Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine

    Polypeptides: Phenylalanine-4-hydroxylaseSynonyms: Phe-4-monooxygenase
  5. Target

    Glutamate receptor 4

    go.drugbank.com/bio_entities/BE0000830
    TargetHumans

    Ionotropic glutamate receptor that functions as a ligand-gated cation channel, gated by L-glutamate and glutamatergic agonists such as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), quisqualic

    Polypeptides: Glutamate receptor 4Synonyms: GluR-4, AMPA-selective glutamate receptor 4
  6. Target

    4-alpha-glucanotransferase

    go.drugbank.com/bio_entities/BE0001664
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Polypeptides: 4-alpha-glucanotransferaseFunction: 4-alpha-glucanotransferase activity
  7. Target

    Endoglucanase E-4

    go.drugbank.com/bio_entities/BE0003251
    TargetThermomonospora fusca

    Polypeptides: Endoglucanase E-4Synonyms: Cellulase E-4, Endo-1,4-beta-glucanase E-4
  8. Target

    Aminoglycoside nucleotidyltransferase (4')

    go.drugbank.com/bio_entities/BE0003547
    EnzymeStaphylococcus aureus

    Inactivates the antibiotic kanamycin by catalyzing the transfer of a nucleotidyl group from nucleoside triphosphates such as ATP to the 4'-hydroxyl group of the aminoglycoside.

    Polypeptides: Aminoglycoside nucleotidyltransferase (4')Synonyms: ANT(4')
  9. Target

    Pepsin A-4

    go.drugbank.com/bio_entities/BE0012524
    TargetHumans

    Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent

    Polypeptides: Pepsin A-4Synonyms: Pepsinogen-4
  10. Target

    Interferon alpha-4

    go.drugbank.com/bio_entities/BE0012570
    TargetHumans

    Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase

    Polypeptides: Interferon alpha-4Synonyms: IFN-alpha-4