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Quazepam Action Pathway
smpdb.ca/view/SMP0126138Drug actionLike other benzodiazepines, quazepam likely exerts its effects by potentiating the effect of gamma-aminobutyric acid (GABA) on GABA(A) receptors, the main inhibitory neurotransmitter receptors in the mammalian
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Remimazolam Action Pathway
smpdb.ca/view/SMP0126145Drug actionLike other benzodiazepines, remimazolam exerts its therapeutic effects by potentiating the effect of gamma-aminobutyric acid (GABA) on GABA(A) receptors, the main inhibitory neurotransmitter receptors
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate +2 moreEnzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Talbutal Action Pathway
smpdb.ca/view/SMP0126147Drug actionTalbutal, also called 5-allyl-5-sec-butylbarbituric acid, is a barbiturate with a short to intermediate duration of action. It is a nonselective central nervous system (CNS) depressant.
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Nitrazepam Action Pathway
smpdb.ca/view/SMP0126164Drug actionThis drug affects central benzodiazepine receptors, which are associated with inhibitory GABA (gamma amino butyric acid)receptors, leading to enhanced GABA binding activity.
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Phenobarbital Action Pathway
smpdb.ca/view/SMP0126831Drug actionFunctioning as a nonselective depressant of the central nervous system, it engages inhibitory gamma-aminobutyric acid subtype receptors, thereby modulating chloride currents across receptor channels and … Phenobarbital is absorbed to varying degrees through oral, rectal, or parenteral routes, with the salts exhibiting quicker absorption compared to the acids.
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Phenobarbital · Calcium · Magnesium cation +3 moreEnzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Zopiclone Action Pathway
smpdb.ca/view/SMP0126832Drug actionOperating outside the benzodiazepine and barbiturate realms, it interacts with the gamma-aminobutyric acid-benzodiazepine (GABABZ) receptor complex, demonstrating both benzodiazepine-like and some barbiturate-like
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2GABA
smpdb.ca/view/SMP0127038PhysiologicalGamma-aminobutyric acid (GABA) is an amino acid that serves as the primary inhibitory neurotransmitter in the brain and a major inhibitory neurotransmitter in the spinal cord. … After synthesis, it is loaded into synaptic vesicles by the vesicular inhibitory amino acid transporter. SNARE complexes help dock the vesicles into the plasma membrane of the cell.
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate +2 moreEnzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Lorazepam Action Pathway
smpdb.ca/view/SMP0125053Drug actionLorazepam is a short-acting benzodiazepine commonly used for the short-term relief of anxiety symptoms related to anxiety disorders and anxiety associated with depressive symptoms such as anxiety-associated insomnia. It is as well used a...
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Clonazepam Action Pathway
smpdb.ca/view/SMP0125054Drug actionClonazepam is a long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, and seizures. Clonazepam ballosterically binds on the benzodiazepine receptors in the post-synaptic GABA-A ligand-...
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Midazolam Action Pathway
smpdb.ca/view/SMP0125055Drug actionMidazolam is a short-acting injectable benzodiazepine with rapid onset that is commonly used in seizures, anesthesia and anxiety disorders. Midazolam allosterically binds on the benzodiazepine receptors in the post-synaptic GABA-A ligand...
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2