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Displaying results 61 - 70 of 302 in total
  1. Pathway

    Mitochondrial Complex II Deficiency

    smpdb.ca/view/SMP0000548
    Disease

    Interestingly, complex II deficiency gene mutation carriers may be at an increased risk for certain cancers. … Because complex II is found in the mitochondria, CII deficiency is technically considered a mitochondrial disease.

    Drugs: Pyruvic acid · Biotin · Succinic acid · NADH · ATP · Magnesium cation +4 more
    Enzymes: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
  2. Pathway

    Copper gluconate Drug Metabolism

    smpdb.ca/view/SMP0130548
    Metabolic

    Copper gluconate passes through the liver and is then excreted from the body mainly through the kidney. … Copper gluconate is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Copper gluconate
  3. Drug

    Quaratusugene ozeplasmid

    go.drugbank.com/drugs/DB19231
    Investigational

    Quaratusugene ozeplasmid is under investigation in clinical trial NCT05062980 (Quaratusugene Ozeplasmid (Reqorsa) in Combination With Pembrolizumab in Previously Treated Non-small Lung Cancer).

    Synonyms: Dna-lipid complex (dotap/cholesterol) plasmid vector (plj143/pkgb2/tusc2, baylor) expressing the tusc2 gene
  4. Drug

    2-(4-hydroxyphenyl)benzo[b]thiophen-6-ol

    go.drugbank.com/drugs/DB08773
    Experimental

    Synonyms: Raloxifene core
  5. Pathway

    2-Ketoglutarate Dehydrogenase Complex Deficiency

    smpdb.ca/view/SMP0125755
    Disease

    oxoglutarate dehydrogenase complex (OGDC). … 2-Ketoglutarate dehydrogenase complex deficiency, also known as alpha-ketoglutarate dehydrogenase deficiency or oxoglutaric aciduria, is an autosomal recessive disorder of the Krebs cycle caused by a defective

    Drugs: Pyruvic acid · Biotin · Succinic acid · NADH · ATP · Magnesium cation +4 more
    Enzymes: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
  6. Pathway

    Undecoylium chloride iodine complex Drug Metabolism

    smpdb.ca/view/SMP0130610
    Metabolic

    Undecoylium chloride iodine complex passes through the liver and is then excreted from the body mainly through the kidney. … Undecoylium chloride iodine complex is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Undecoylium chloride iodine complex
  7. Pathway

    Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate Drug Metabolism

    smpdb.ca/view/SMP0130603
    Metabolic

    Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate passes through the liver and is then excreted from the body mainly through the kidney. … Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate
  8. Drug

    Livmoniplimab

    go.drugbank.com/drugs/DB18939
    Investigational

    Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solu...

    Synonyms: Immunoglobulin g4 (234-proline), anti-(human protein garp-transforming growth factor .beta.1 complex) (human monoclonal abbv-151 .gamma.4-chain), disulfide with human monoclonal abbv-151 .kappa.
  9. Drug

    Polyinosinic-polycytidylic acid

    go.drugbank.com/drugs/DB16467
    Investigational

    Synonyms: Polyinosinic-polycytidylic acid complex
  10. Drug

    Demplatin pegraglumer

    go.drugbank.com/drugs/DB14807
    Investigational

    Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).

    Synonyms: A micelle drug formulation composed of cisplatin and mPEG-poly(l-Glu) diblock copolymer with 1,3-propanediyl linkagecisplatin is incorporated in polymeric micelles via polymer-metal complex formation with